Literature DB >> 35188820

Anterior Mediastinal Neuroblastoma Associated with Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Morphologic, Immunohistochemical, and Genetic Case Report and Review of the Literature.

Gregory T Kennedy1, Christopher M Sande1, Lea F Surrey2, Feredun S Azari1, Charuhas Deshpande1, Sunil Singhal1.   

Abstract

We report a mediastinal neuroblastoma in an octogenarian with paraneoplastic syndrome of inappropriate antidiuretic hormone secretion (SIADH). Neuroblastomas are very rare tumors in adults, with thoracic or mediastinal locations being especially uncommon. These neoplasms have been occasionally associated with the SIADH. Given the rarity of incidence and paucity of diagnostic and outcomes data, the significance of standard neuroblastoma prognostic characteristics is unclear, and no treatment paradigms exist for these patients. Further studies are needed to inform future clinical guidelines.

Entities:  

Keywords:  immunophenotypic characterization; mediastinal tumors; neuroblastoma; paraneoplastic syndrome; thoracic surgery

Mesh:

Substances:

Year:  2022        PMID: 35188820      PMCID: PMC9357129          DOI: 10.1177/10668969221080061

Source DB:  PubMed          Journal:  Int J Surg Pathol        ISSN: 1066-8969            Impact factor:   1.358


  17 in total

1.  Neuroblastoma in adults: Incidence and survival analysis based on SEER data.

Authors:  Natia Esiashvili; Michael Goodman; Kevin Ward; Robert B Marcus; Peter A S Johnstone
Journal:  Pediatr Blood Cancer       Date:  2007-07       Impact factor: 3.167

2.  Thymic neuroblastoma in adults: report of three cases with special emphasis on its association with the syndrome of inappropriate secretion of antidiuretic hormone.

Authors:  P Argani; R A Erlandson; J Rosai
Journal:  Am J Clin Pathol       Date:  1997-11       Impact factor: 2.493

3.  PHOX2B reliably distinguishes neuroblastoma among small round blue cell tumours.

Authors:  Yin P Hung; John P Lee; Andrew M Bellizzi; Jason L Hornick
Journal:  Histopathology       Date:  2017-09-06       Impact factor: 5.087

4.  Neuroblastoma of the anterior mediastinum in an 80-year-old woman.

Authors:  J E Salter; D Gibson; N G Ordóñez; B Mackay
Journal:  Ultrastruct Pathol       Date:  1995 Jul-Aug       Impact factor: 1.094

5.  Expression pattern of ISL-1, TTF-1 and PAX5 in olfactory neuroblastoma.

Authors:  P Czapiewski; A Gorczyński; J Haybaeck; K Okoń; J Reszeć; W Skrzypczak; J Dzierżanowski; M Kunc; J Karczewska; W Biernat
Journal:  Pol J Pathol       Date:  2016-06       Impact factor: 1.072

6.  Ataxia induced by a thymic neuroblastoma in the elderly patient.

Authors:  Ory Wiesel; Shamik Bhattacharyya; Henrikas Vaitkevicius; Sashank Prasad; Ciaran McNamee
Journal:  World J Surg Oncol       Date:  2015-05-12       Impact factor: 2.754

7.  A case report of a thymic neuroblastoma associated with syndrome of inappropriate secretion of antidiuretic hormone: Ten-year follow-up results after surgical treatment.

Authors:  Yukitoshi Satoh
Journal:  Int J Surg Case Rep       Date:  2019-04-05

8.  Neuroblastoma in the Elderly and SIADH: Case Report and Review of the Literature.

Authors:  Micaela Pellegrino; Laura Gianotti; Sara Cassibba; Rodolfo Brizio; Alberto Terzi; Giorgio Borretta
Journal:  Case Rep Med       Date:  2012-08-23

9.  Neuroblastoma of the elderly, an oncologist's nightmare: case presentation, literature review and SEER database analysis.

Authors:  Elisa Rogowitz; Hani M Babiker; Mohammed Kanaan; Rebecca A Millius; Q Scott Ringenberg; Maria Bishop
Journal:  Exp Hematol Oncol       Date:  2014-07-17

Review 10.  Histone methyltransferase SETD2: a potential tumor suppressor in solid cancers.

Authors:  Rui Chen; Wei-Qing Zhao; Cheng Fang; Xin Yang; Mei Ji
Journal:  J Cancer       Date:  2020-03-05       Impact factor: 4.207

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