| Literature DB >> 3518604 |
Abstract
Interleukins are polypeptides that act on leukocytes and other tissue targets. Interleukin-1, produced by macrophages and other cells, activates lymphocytes and also induces several components of the host's acute-phase response to infection and injury. Interleukin-2, produced by T lymphocytes, is a growth factor for helper, suppressor, and cytotoxic T lymphocytes. By several criteria, interleukins can be considered the hormones that regulate immune and inflammatory responses.Entities:
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Year: 1986 PMID: 3518604 DOI: 10.1146/annurev.me.37.020186.001133
Source DB: PubMed Journal: Annu Rev Med ISSN: 0066-4219 Impact factor: 13.739