Literature DB >> 35183369

Re: Use of mouthwashes against COVID-19 in dentistry.

Duo Li1, Liu Yang2.   

Abstract

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Year:  2021        PMID: 35183369      PMCID: PMC8638215          DOI: 10.1016/j.bjoms.2021.08.012

Source DB:  PubMed          Journal:  Br J Oral Maxillofac Surg        ISSN: 0266-4356            Impact factor:   2.018


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Sir, We have read with great interest the article published in the British Journal of Oral and Maxillofacial Surgery by Vergara-Buenaventura and Castro-Ruiz stating that although there is still no clinical evidence that they can prevent the transmission of SARS-CoV-2, preoperative antimicrobial mouth rinses with chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), povidone-iodine (PVP-I), and hydrogen peroxide (H2O2) have been recommended to reduce the number of micro-organisms in aerosols and drops during oral procedures. Sodium hypochlorite (NaOCI) is also widely accepted as being a safe and effective antiseptic against bacteria, fungi, and viruses. The findings confirm the effectiveness of mouth rinse with dilute sodium hypochlorite against bacterial biofilms and the significant reductions in gingival inflammation.[2], [3] Meanwhile, as the effectiveness of sodium hypochlorite against viruses, including feline calicivirus, human influenza virus, measles virus, human herpesvirus, human adenovirus, and murine hepatitis virus, which have many structural and genetic similarities to SARS-CoV, has been suggested, it is likely that it should also effectively inactivate SARS-CoV-2.[4], [5] Mouthwashes of dilute sodium hypochlorite should therefore be fully recommended as an effective prevention of coronavirus before the treatment of oral diseases during the COVID-19 outbreak.

Conflict of interest

We have no conflicts of interest.

Ethics statement/confirmation of patients’ permission

Not applicable.
  5 in total

1.  Evaluation of the antiviral activity of chlorine dioxide and sodium hypochlorite against feline calicivirus, human influenza virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus and canine parvovirus.

Authors:  Takeshi Sanekata; Toshiaki Fukuda; Takanori Miura; Hirofumi Morino; Cheolsung Lee; Ken Maeda; Kazuko Araki; Toru Otake; Takuya Kawahata; Takashi Shibata
Journal:  Biocontrol Sci       Date:  2010-06       Impact factor: 0.982

Review 2.  Sodium hypochlorite (dilute chlorine bleach) oral rinse in patient self-care.

Authors:  Sandra K Rich; Jørgen Slots
Journal:  J West Soc Periodontol Periodontal Abstr       Date:  2015

3.  Evaluation of the effects of 0.05% sodium hypochlorite and 0.12% chlorhexidine gluconate twice daily rinse on periodontal parameters and gingival crevicular fluid HSV1 and CMV levels in patients with chronic periodontitis: a multicentric study.

Authors:  Sangeeta Singh; Parul Sharma; Mahadevan Kumar
Journal:  Med J Armed Forces India       Date:  2020-10-24

Review 4.  Use of mouthwashes against COVID-19 in dentistry.

Authors:  A Vergara-Buenaventura; C Castro-Ruiz
Journal:  Br J Oral Maxillofac Surg       Date:  2020-08-15       Impact factor: 1.651

5.  The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.

Authors:  Christine Dellanno; Quinn Vega; Diane Boesenberg
Journal:  Am J Infect Control       Date:  2009-08-18       Impact factor: 2.918

  5 in total

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