Takeshi Kera1, Hisashi Kawai2, Junta Takahashi3, Hirohiko Hirano4, Yutaka Watanabe5, Yoshinori Fujiwara6, Kazushige Ihara7, Hunkyung Kim8, Shuichi Obuchi9. 1. Department of Physical Therapy, Takasaki University of Health and Welfare, Gunma, Japan; Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: kera@takasaki-u.ac.jp. 2. Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: hkawai@tmig.or.jp. 3. The Tokyo Metropolitan Support Center for Promotion of Preventive Care, Tokyo, Japan. Electronic address: junta@tmig.or.jp. 4. Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: h-hiro@gd5.so-net.ne.jp. 5. Gerodontology, Department of Oral Health Science, Faculty of Dental Medicine, Hokkaido University, Hokkaido, Japan. Electronic address: ywata@den.hokudai.ac.jp. 6. Research Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: fujiwayo@tmig.or.jp. 7. Department of Social Medicine, Hirosaki University School of Medicine, Aomori, Japan. Electronic address: ihara@hirosaki-u.ac.jp. 8. Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: kimhk@tmig.or.jp. 9. Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. Electronic address: obuchipc@tmig.or.jp.
Abstract
BACKGROUND: Ground reaction force during sit-to-stand motion is related to lower extremity strength, and such measurements indicating weak muscle strength, may be linked to sarcopenia. We aimed to examine and describe the relationship between sarcopenia and ground reaction force during sit-to-stand motion to develop a diagnostic tool. RESEARCH QUESTION: Can ground reaction force during sit-to-stand motion help detect sarcopenia? METHODS: This study included 627 community-dwelling older adults who were divided into non-sarcopenia and sarcopenia groups to compare ground reaction force parameters. A sit-to-stand force analyzer was used to measure the ground reaction force, power, and time between the minimum and maximum ground reaction force. We assessed the association between sarcopenia and each ground reaction force parameter. Receiver operating characteristic curve analysis was performed with sarcopenia as the dependent variable and ground reaction force-related measurements as independent variables. The probability of predicting sarcopenia was calculated using multiple logistic regression analysis, with sex and age as independent variables, and another receiver operating characteristic analysis was performed using the probability value. RESULTS: Ground reaction force parameters related to strength and power were lower in the sarcopenia group than in the non-sarcopenia group. Furthermore, we were able to develop a formula to detect sarcopenia using the maximum ground reaction force (area under the curve; 0.906 [95% CI 0.858-0.954] for men and 0.858 [0.808-0.908] for women). The sensitivity and specificity of sarcopenia detection using this formula were 89.7% and 80.5%, respectively, for men and 95.0% and 60.9%, respectively, for women. SIGNIFICANCE: Ground reaction force during sit-to-stand motion may reflect low skeletal muscle strength associated with sarcopenia. We were able to develop a method for sarcopenia detection by analyzing the sit-to-stand force required in only one or two sit-to-stand motions, even though it does not measure the skeletal muscle mass directly.
BACKGROUND: Ground reaction force during sit-to-stand motion is related to lower extremity strength, and such measurements indicating weak muscle strength, may be linked to sarcopenia. We aimed to examine and describe the relationship between sarcopenia and ground reaction force during sit-to-stand motion to develop a diagnostic tool. RESEARCH QUESTION: Can ground reaction force during sit-to-stand motion help detect sarcopenia? METHODS: This study included 627 community-dwelling older adults who were divided into non-sarcopenia and sarcopenia groups to compare ground reaction force parameters. A sit-to-stand force analyzer was used to measure the ground reaction force, power, and time between the minimum and maximum ground reaction force. We assessed the association between sarcopenia and each ground reaction force parameter. Receiver operating characteristic curve analysis was performed with sarcopenia as the dependent variable and ground reaction force-related measurements as independent variables. The probability of predicting sarcopenia was calculated using multiple logistic regression analysis, with sex and age as independent variables, and another receiver operating characteristic analysis was performed using the probability value. RESULTS: Ground reaction force parameters related to strength and power were lower in the sarcopenia group than in the non-sarcopenia group. Furthermore, we were able to develop a formula to detect sarcopenia using the maximum ground reaction force (area under the curve; 0.906 [95% CI 0.858-0.954] for men and 0.858 [0.808-0.908] for women). The sensitivity and specificity of sarcopenia detection using this formula were 89.7% and 80.5%, respectively, for men and 95.0% and 60.9%, respectively, for women. SIGNIFICANCE: Ground reaction force during sit-to-stand motion may reflect low skeletal muscle strength associated with sarcopenia. We were able to develop a method for sarcopenia detection by analyzing the sit-to-stand force required in only one or two sit-to-stand motions, even though it does not measure the skeletal muscle mass directly.
Authors: Alessio Montemurro; Juan D Ruiz-Cárdenas; María Del Mar Martínez-García; Juan J Rodríguez-Juan Journal: Sensors (Basel) Date: 2022-08-11 Impact factor: 3.847