BACKGROUND: Patients undergoing left ventricular assist device (LVAD) implantation are at risk for death and postoperative adverse outcomes. Interhospital variability and concordance of quality metrics were assessed using the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs). METHODS: A total of 22 173 patients underwent primary, durable LVAD implantation across 160 hospitals from 2012 to 2020, excluding hospitals performing <10 implant procedures. Observed and risk-adjusted operative mortality rates were calculated for each hospital. Outcomes included operative and 90-day mortality, a composite of adverse events (operative mortality, bleeding, stroke, device malfunction, renal dysfunction, respiratory failure), and secondarily failure to rescue. Rates are presented as median (interquartile range [IQR]). Hospital performance was evaluated using observed-to-expected (O/E) ratios for mortality and the composite outcome. RESULTS: Interhospital variability existed in observed (median, 7.2% [IQR, 5.1%-9.6%]) mortality. The rates of adverse events varied across hospitals: major bleeding, 15.6% (IQR, 11.4%-22.4%); stroke, 3.1% (IQR, 1.6%-4.7%); device malfunction, 2.4% (IQR, 0.8%-3.7%); respiratory failure, 10.5% (IQR, 4.6%-15.7%); and renal dysfunction, 6.4% (IQR, 3.2%-9.6%). The O/E ratio for operative mortality varied from 0.0 to 6.1, whereas the O/E ratio for the composite outcome varied from 0.28 to 1.99. Hospital operative mortality O/E ratios were more closely correlated with the 90-day mortality O/E ratio (r = 0.74) than with the composite O/E ratio (r = 0.12). CONCLUSIONS: This study reported substantial interhospital variability in performance for hospitals implanting durable LVADs. These findings support the need to (1) report hospital-level performance (mortality, composite) and (2) undertake benchmarking activities to reduce unwarranted variability in outcomes.
BACKGROUND: Patients undergoing left ventricular assist device (LVAD) implantation are at risk for death and postoperative adverse outcomes. Interhospital variability and concordance of quality metrics were assessed using the Society of Thoracic Surgeons Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs). METHODS: A total of 22 173 patients underwent primary, durable LVAD implantation across 160 hospitals from 2012 to 2020, excluding hospitals performing <10 implant procedures. Observed and risk-adjusted operative mortality rates were calculated for each hospital. Outcomes included operative and 90-day mortality, a composite of adverse events (operative mortality, bleeding, stroke, device malfunction, renal dysfunction, respiratory failure), and secondarily failure to rescue. Rates are presented as median (interquartile range [IQR]). Hospital performance was evaluated using observed-to-expected (O/E) ratios for mortality and the composite outcome. RESULTS: Interhospital variability existed in observed (median, 7.2% [IQR, 5.1%-9.6%]) mortality. The rates of adverse events varied across hospitals: major bleeding, 15.6% (IQR, 11.4%-22.4%); stroke, 3.1% (IQR, 1.6%-4.7%); device malfunction, 2.4% (IQR, 0.8%-3.7%); respiratory failure, 10.5% (IQR, 4.6%-15.7%); and renal dysfunction, 6.4% (IQR, 3.2%-9.6%). The O/E ratio for operative mortality varied from 0.0 to 6.1, whereas the O/E ratio for the composite outcome varied from 0.28 to 1.99. Hospital operative mortality O/E ratios were more closely correlated with the 90-day mortality O/E ratio (r = 0.74) than with the composite O/E ratio (r = 0.12). CONCLUSIONS: This study reported substantial interhospital variability in performance for hospitals implanting durable LVADs. These findings support the need to (1) report hospital-level performance (mortality, composite) and (2) undertake benchmarking activities to reduce unwarranted variability in outcomes.
Authors: Donald S Likosky; Steven D Harrington; Lourdes Cabrera; Alphonse DeLucia; Carol E Chenoweth; Sarah L Krein; Dylan Thibault; Min Zhang; Roland A Matsouaka; Raymond J Strobel; Richard L Prager Journal: Circ Cardiovasc Qual Outcomes Date: 2018-11
Authors: Manreet K Kanwar; Colleen K McIlvennan; Lisa C Lohmueller; Stephen H Bailey; Joseph G Rogers; Jeffrey Teuteberg; Jennifer Cowger Journal: ASAIO J Date: 2021-04-01 Impact factor: 2.872
Authors: Jeffrey J Teuteberg; Joseph C Cleveland; Jennifer Cowger; Robert S Higgins; Daniel J Goldstein; Mary Keebler; James K Kirklin; Susan L Myers; Christopher T Salerno; Josef Stehlik; Felix Fernandez; Vinay Badhwar; Francis D Pagani; Pavan Atluri Journal: Ann Thorac Surg Date: 2020-03 Impact factor: 4.330
Authors: David M Shahian; Sean M O'Brien; Giovanni Filardo; Victor A Ferraris; Constance K Haan; Jeffrey B Rich; Sharon-Lise T Normand; Elizabeth R DeLong; Cynthia M Shewan; Rachel S Dokholyan; Eric D Peterson; Fred H Edwards; Richard P Anderson Journal: Ann Thorac Surg Date: 2009-07 Impact factor: 4.330
Authors: Ezequiel J Molina; Palak Shah; Michael S Kiernan; William K Cornwell; Hannah Copeland; Koji Takeda; Felix G Fernandez; Vinay Badhwar; Robert H Habib; Jeffrey P Jacobs; Devin Koehl; James K Kirklin; Francis D Pagani; Jennifer A Cowger Journal: Ann Thorac Surg Date: 2021-01-16 Impact factor: 4.330
Authors: Donald S Likosky; Raymond J Strobel; Xiaoting Wu; Robert S Kramer; Baron L Hamman; James K Brevig; Michael P Thompson; Amir A Ghaferi; Min Zhang; Eric J Lehr Journal: J Thorac Cardiovasc Surg Date: 2021-01-29 Impact factor: 6.439
Authors: David M Shahian; Michael E Bowdish; Jordan P Bloom; Moritz C Wyler von Ballmoos; James R Edgerton; Mark S Antman; Paul A Kurlansky; Kevin W Lobdell; Joseph C Cleveland; Mario F L Gaudino; Gaetano Paone; Christina Vassileva; Vinod H Thourani; Anthony P Furnary; Vinay Badhwar; Jeffrey P Jacobs; Sean M O'Brien Journal: Ann Thorac Surg Date: 2021-07-17 Impact factor: 4.330