Literature DB >> 35174734

Improving Awareness Could Transform Outcomes in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 1].

Benjamin M Davies1,2, Oliver Mowforth1,2, Helen Wood1, Zahabiya Karimi1, Iwan Sadler1, Lindsay Tetreault3, Jamie Milligan4, Jamie R F Wilson5, Sukhvinder Kalsi-Ryan6,7, Julio C Furlan6,7, Yoshiharu Kawaguchi8, Manabu Ito9, Carl Moritz Zipser10, Timothy F Boerger11, Alexander R Vaccaro12, Rory K J Murphy13, Mike Hutton14, Ricardo Rodrigues-Pinto15,16, Paul A Koljonen17, James S Harrop18, Bizhan Aarabi19, Vafa Rahimi-Movaghar20, Shekar N Kurpad11, James D Guest21, Jefferson R Wilson22, Brian K Kwon23, Mark R N Kotter1,2, Michael G Fehlings22.   

Abstract

STUDY
DESIGN: Literature Review (Narrative).
OBJECTIVE: To introduce the number one research priority for Degenerative Cervical Myelopathy (DCM): Raising Awareness.
METHODS: Raising awareness has been recognized by AO Spine RECODE-DCM as the number one research priority. This article reviews the evidence that awareness is low, the potential drivers, and why this must be addressed. Case studies of success from other diseases are also reviewed, drawing potential parallels and opportunities for DCM.
RESULTS: DCM may affect as many as 1 in 50 adults, yet few will receive a diagnosis and those that do will wait many years for it. This leads to poorer outcomes from surgery and greater disability. DCM is rarely featured in healthcare professional training programs and has received relatively little research funding (<2% of Amyotrophic Lateral Sclerosis or Multiple Sclerosis over the last 25 years). The transformation of stroke and acute coronary syndrome services, from a position of best supportive care with occasional surgery over 50 years ago, to avoidable disability today, represents transferable examples of success and potential opportunities for DCM. Central to this is raising awareness.
CONCLUSION: Despite the devastating burden on the patient, recognition across research, clinical practice, and healthcare policy are limited. DCM represents a significant unmet need that must become an international public health priority.

Entities:  

Keywords:  cervical; degenerative cervical myelopathy; disability; disc herniation; myelopathy; ossification posterior longitudinal ligament; policy; prioritization; research prioritization; review; spondylosis; spondylotic; stenosis

Year:  2022        PMID: 35174734      PMCID: PMC8859708          DOI: 10.1177/21925682211050927

Source DB:  PubMed          Journal:  Global Spine J        ISSN: 2192-5682


  89 in total

1.  Burden of disease: medical and economic impact of acute coronary syndromes.

Authors:  Alexander G G Turpie
Journal:  Am J Manag Care       Date:  2006-12       Impact factor: 2.229

2.  Surgery for degenerative cervical myelopathy: a patient-centered quality of life and health economic evaluation.

Authors:  Christopher D Witiw; Lindsay A Tetreault; Fabrice Smieliauskas; Branko Kopjar; Eric M Massicotte; Michael G Fehlings
Journal:  Spine J       Date:  2016-10-25       Impact factor: 4.166

3.  Is Preoperative Duration of Symptoms a Significant Predictor of Functional Outcomes in Patients Undergoing Surgery for the Treatment of Degenerative Cervical Myelopathy?

Authors:  Lindsay Tetreault; Jefferson R Wilson; Mark R N Kotter; Pierre Côté; Aria Nouri; Branko Kopjar; Paul M Arnold; Michael G Fehlings
Journal:  Neurosurgery       Date:  2019-11-01       Impact factor: 4.654

Review 4.  Systematic review of magnetic resonance imaging characteristics that affect treatment decision making and predict clinical outcome in patients with cervical spondylotic myelopathy.

Authors:  Lindsay A Tetreault; Joseph R Dettori; Jefferson R Wilson; Anoushka Singh; Aria Nouri; Michael G Fehlings; Erika D Brodt; W Bradley Jacobs
Journal:  Spine (Phila Pa 1976)       Date:  2013-10-15       Impact factor: 3.468

Review 5.  History, Evolution, and Importance of Emergency Endovascular Treatment of Acute Ischemic Stroke.

Authors:  Jessalyn K Holodinsky; Amy Y X Yu; Zarina A Assis; Abdulaziz S Al Sultan; Bijoy K Menon; Andrew M Demchuk; Mayank Goyal; Michael D Hill
Journal:  Curr Neurol Neurosci Rep       Date:  2016-05       Impact factor: 5.081

6.  Diagnostic accuracy of clinical tools for assessment of acute stroke: a systematic review.

Authors:  Daria Antipova; Leila Eadie; Ashish Macaden; Philip Wilson
Journal:  BMC Emerg Med       Date:  2019-09-04

7.  Posterior Surgical Techniques for Cervical Spondylotic Myelopathy: WFNS Spine Committee Recommendations.

Authors:  Abdul Hafid Bajamal; Se-Hoon Kim; Mohammad Reza Arifianto; Muhammad Faris; Eko Agus Subagio; Ben Roitberg; Inyang Udo-Inyang; Jonathan Belding; Mehmet Zileli; Jutty K B C Parthiban
Journal:  Neurospine       Date:  2019-09-30

8.  Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services.

Authors:  A J Coull; J K Lovett; P M Rothwell
Journal:  BMJ       Date:  2004-01-26

Review 9.  Clinical neurology: why this still matters in the 21st century.

Authors:  David J Nicholl; Jason P Appleton
Journal:  J Neurol Neurosurg Psychiatry       Date:  2014-05-29       Impact factor: 10.154

10.  Outcomes of Degenerative Cervical Myelopathy From The Perspective of Persons Living With the Condition: Findings of a Semistructured Interview Process With Partnered Internet Survey.

Authors:  Benjamin M Davies; Colin Munro; Danyal Z Khan; Siobhan M Fitzpatrick; Bryn Hilton; Oliver D Mowforth; Angus G K McNair; Iwan Sadler; Mark R N Kotter
Journal:  Global Spine J       Date:  2020-11-18
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  2 in total

1.  Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS).

Authors:  Benjamin M Davies; Alvaro Yanez Touzet; Oliver D Mowforth; Keng Siang Lee; Danyal Khan; Julio C Furlan; Michael G Fehlings; James S Harrop; Carl Moritz Zipser; Ricardo Rodrigues-Pinto; James Milligan; Ellen Sarewitz; Armin Curt; Vafa Rahimi-Movaghar; Bizhan Aarabi; Timothy F Boerger; Lindsay Tetreault; Robert Chen; James D Guest; Sukhvinder Kalsi-Ryan; Iwan Sadler; Shirley Widdop; Angus G K McNair; Brian K Kwon; Mark R N Kotter
Journal:  BMJ Open       Date:  2022-06-09       Impact factor: 3.006

2.  Proposing a Framework to Understand the Role of Imaging in Degenerative Cervical Myelopathy: Enhancement of MRI Protocols Needed for Accurate Diagnosis and Evaluation.

Authors:  Carl M Zipser; Michael G Fehlings; Konstantinos Margetis; Armin Curt; Michael Betz; Iwan Sadler; Lindsay Tetreault; Benjamin M Davies
Journal:  Spine (Phila Pa 1976)       Date:  2022-06-29       Impact factor: 3.241

  2 in total

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