Literature DB >> 35174533

Seven cases of contact dermatitis due to stearyl alcohol contained in topical medications.

Kazue Nishioka1, Akiko Koizumi1, Yuko Takita1.   

Abstract

Stearyl alcohol is found in various cosmetics and topical medications and is regarded as safe. Allergic contact dermatitis is reported due to this chemical on rare occasions. We report seven cases, comprising three men and four women aged between 36 and 62 between the years 2013 to 2019, of allergic contact dermatitis due to the use of topical medication, where the patient showed a positive result to a patch test using stearyl alcohol. There were 10 topical medications that we considered to be the cause of this: three were from Oronine® H ointment, two from Eurax® cream, one from Eurax H cream, and four from topical antifungal medications. All these medications contained stearyl alcohol. Seven cases of patch tests with stearyl alcohol all showed positive results. Moreover, having done a patch test with cetyl alcohol, two out of three tests showed positive. When researching allergic contact dermatitis due to topical medications, it is important to test for allergy to stearyl alcohol as well as their main ingredients, because it is contained in numerous products and has the ability to cause allergic contact dermatitis.
© 2022 Japanese Dermatological Association.

Entities:  

Keywords:  allergic contact dermatitis; cetyl alcohol; patch testing; stearyl alcohol (CAS 112-92-5); topical medication

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Year:  2022        PMID: 35174533     DOI: 10.1111/1346-8138.16325

Source DB:  PubMed          Journal:  J Dermatol        ISSN: 0385-2407            Impact factor:   4.005


  1 in total

Review 1.  Moisturizer in Patients with Inflammatory Skin Diseases.

Authors:  Seok-Young Kang; Ji-Young Um; Bo-Young Chung; So-Yeon Lee; Jin-Seo Park; Jin-Cheol Kim; Chun-Wook Park; Hye-One Kim
Journal:  Medicina (Kaunas)       Date:  2022-07-01       Impact factor: 2.948

  1 in total

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