Literature DB >> 35173902

Persistent, neuropathic-like trigeminal pain after dental implant loading.

Ndiaye Amadou-Diaw1, Adeline Braud2, Yves Boucher3.   

Abstract

BACKGROUND: Painful post-traumatic trigeminal neuropathy (PTTN) is a known complication of dental implant therapy. Besides cases resulting of nerve damage during surgery or implant placement, some patients report delayed neuropathic-like symptoms only after implant loading i.e. crown placement. The present retrospective study aimed at describing the clinical features of pain experienced by these patients.
MATERIAL AND METHODS: The cohort of patients consulting for chronic orofacial pain at the Groupe Hospitalier Pitié-Salpêtrière (Paris, France) between 2015 and 2020 (ABCD study, IRB # TPS 1106180), was screened for patients with history of dental implant placement and persistent pain. Patients with no pain after surgery for 6 months and pain resulting from the loading of the implant, were included.
RESULTS: Among 675 files of patients screened, 5 fulfilled inclusion criteria. All patients were women, mean age 62.4 ± 9.8 y.o, and reported trigeminal neuropathic-like persistent pain. Intensity of pain was described as moderate to severe, with pin and needles, burning and tingling, and electric shocks as main symptoms.
CONCLUSIONS: These results suggest that implant loading can trigger trigeminal neuropathy, in a previously sensitized nerve. Putative neurophysiological basis of the phenomenon is discussed. Key words:Neuropathic pain, trigeminal nerve, lesion, dental implant, implant loading, allodynia. Copyright:
© 2022 Medicina Oral S.L.

Entities:  

Year:  2022        PMID: 35173902      PMCID: PMC8842286          DOI: 10.4317/jced.59248

Source DB:  PubMed          Journal:  J Clin Exp Dent        ISSN: 1989-5488


  47 in total

Review 1.  Molecular mechanisms of painful traumatic trigeminal neuropathy-Evidence from animal research and clinical correlates.

Authors:  Olga A Korczeniewska; Junad Khan; Eli Eliav; Rafael Benoliel
Journal:  J Oral Pathol Med       Date:  2020-07-04       Impact factor: 4.253

Review 2.  Neuropathic orofacial pain: Facts and fiction.

Authors:  Lene Baad-Hansen; Rafael Benoliel
Journal:  Cephalalgia       Date:  2017-04-12       Impact factor: 6.292

Review 3.  PKCγ interneurons, a gateway to pathological pain in the dorsal horn.

Authors:  Alain Artola; Daniel Voisin; Radhouane Dallel
Journal:  J Neural Transm (Vienna)       Date:  2020-02-27       Impact factor: 3.575

4.  Hedgehog Pathway-Mediated Vascular Alterations Following Trigeminal Nerve Injury.

Authors:  N Moreau; W Dieb; A Mauborgne; S Bourgoin; L Villanueva; M Pohl; Y Boucher
Journal:  J Dent Res       Date:  2016-11-19       Impact factor: 6.116

5.  Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition.

Authors: 
Journal:  Cephalalgia       Date:  2018-01       Impact factor: 6.292

6.  Case studies on implant removal influencing the resolution of inferior alveolar nerve injury.

Authors:  N Khawaja; T Renton
Journal:  Br Dent J       Date:  2009-04-11       Impact factor: 1.626

7.  Implication of the chemokine CCL2 in trigeminal nociception and traumatic neuropathic orofacial pain.

Authors:  C Dauvergne; J Molet; A Reaux-Le Goazigo; A Mauborgne; S Mélik-Parsadaniantz; Y Boucher; M Pohl
Journal:  Eur J Pain       Date:  2013-08-05       Impact factor: 3.931

8.  Electrical Synapses are Involved in Orofacial Neuropathic Pain.

Authors:  Omar Ouachikh; Aziz Hafidi; Yves Boucher; Wisam Dieb
Journal:  Neuroscience       Date:  2018-05-07       Impact factor: 3.590

Review 9.  Systematic Review and Meta-Analysis on Incidence of Altered Sensation of Mandibular Implant Surgery.

Authors:  Chia-Shu Lin; Shih-Yun Wu; Hsin-Yi Huang; Yu-Lin Lai
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

10.  Injury of the Inferior Alveolar Nerve during Implant Placement: a Literature Review.

Authors:  Gintaras Juodzbalys; Hom-Lay Wang; Gintautas Sabalys
Journal:  J Oral Maxillofac Res       Date:  2011-04-01
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