Literature DB >> 3516958

The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic.

V L Reynolds, J P McGovren, L H Hurley.   

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Year:  1986        PMID: 3516958     DOI: 10.7164/antibiotics.39.319

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  12 in total

1.  Spectrum of cell-cycle kinetics of alkylating agent adolezesin in gynecological cancer cell lines: correlation with drug-induced cytotoxicity.

Authors:  H N Nguyen; B U Sevin; H Averette; J Perras; R Ramos; D Donato
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  In vitro evaluation of a novel chemotherapeutic agent, Adozelesin, in gynecologic-cancer cell lines.

Authors:  H N Nguyen; B U Sevin; H Averette; J Perras; R Hightower; R Ramos; D Donato; M Penalver
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Demonstration of the asymmetric effect of CC-1065 on local DNA structure using a site-directed adduct in a 117-base-pair fragment from M13mp1.

Authors:  L H Hurley; D R Needham-VanDevanter; C S Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

4.  Sequence-specific arrest of primer extension on single-stranded DNA by an oligonucleotide-minor groove binder conjugate.

Authors:  I Afonina; I Kutyavin; E Lukhtanov; R B Meyer; H Gamper
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

5.  Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

Authors:  J D Jonkman-de Vries; M J de Graaff-Teulen; R E Henrar; J J Kettenes-van den Bosch; A Bult; J H Beijnen
Journal:  Invest New Drugs       Date:  1994       Impact factor: 3.850

6.  A repair competition assay to assess recognition by human nucleotide excision repair.

Authors:  M T Hess; D Gunz; H Naegeli
Journal:  Nucleic Acids Res       Date:  1996-03-01       Impact factor: 16.971

7.  Solution structure of a highly stable DNA duplex conjugated to a minor groove binder.

Authors:  S Kumar; M W Reed; H B Gamper; V V Gorn; E A Lukhtanov; M Foti; J West; R B Meyer; B I Schweitzer
Journal:  Nucleic Acids Res       Date:  1998-02-01       Impact factor: 16.971

8.  Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit.

Authors:  D L Boger; H Zarrinmayeh; S A Munk; P A Kitos; O Suntornwat
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

9.  Rapid and efficient hybridization-triggered crosslinking within a DNA duplex by an oligodeoxyribonucleotide bearing a conjugated cyclopropapyrroloindole.

Authors:  E A Lukhtanov; M A Podyminogin; I V Kutyavin; R B Meyer; H B Gamper
Journal:  Nucleic Acids Res       Date:  1996-02-15       Impact factor: 16.971

10.  End points for biomonitoring: assay sensitivity/selectivity.

Authors:  C S Aaron; D M Zimmer; P R Harbach; R L Yu
Journal:  Environ Health Perspect       Date:  1996-05       Impact factor: 9.031

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