Bryan S Walsh1, Jonathan J Darrow1,2, Aaron S Kesselheim3. 1. Program On Regulation, Therapeutics And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. 2. Department of Law & Taxation, Bentley University, Waltham, MA, USA. 3. Program On Regulation, Therapeutics And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. akesselheim@bwh.harvard.edu.