Literature DB >> 35169281

Synthetic lethal screening identifies DHODH as a target for MEN1-mutated tumor cells.

Yarui Ma1,2, Qing Zhu1,3, Xiaobing Wang1,4, Mei Liu1, Qichen Chen5, Liming Jiang6, Yihebali Chi7, Yi-Xin Zeng8, Hong Zhao9,10, Yuchen Jiao11,12,13.   

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Year:  2022        PMID： 35169281      PMCID： PMC9160065          DOI： 10.1038/s41422-022-00613-1

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   46.297


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  10 in total

Review 1.  The dihydroorotate dehydrogenases: Past and present.

Authors:  Renata A G Reis; Felipe Antunes Calil; Patricia Rosa Feliciano; Matheus Pinto Pinheiro; M Cristina Nonato
Journal:  Arch Biochem Biophys       Date:  2017-06-27       Impact factor: 4.013

Review 2.  Clinical aspects of multiple endocrine neoplasia type 1.

Authors:  Abdallah Al-Salameh; Guillaume Cadiot; Alain Calender; Pierre Goudet; Philippe Chanson
Journal:  Nat Rev Endocrinol       Date:  2021-02-09       Impact factor: 43.330

3.  A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors.

Authors:  J S Crabtree; P C Scacheri; J M Ward; L Garrett-Beal; M R Emmert-Buck; K A Edgemon; D Lorang; S K Libutti; S C Chandrasekharappa; S J Marx; A M Spiegel; F S Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

4.  Dihydroorotat-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides.

Authors:  M Löffler; J Jöckel; G Schuster; C Becker
Journal:  Mol Cell Biochem       Date:  1997-09       Impact factor: 3.396

5.  Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Authors:  Martina Bajzikova; Jaromira Kovarova; Ana R Coelho; Stepana Boukalova; Sehyun Oh; Katerina Rohlenova; David Svec; Sona Hubackova; Berwini Endaya; Kristyna Judasova; Ayenachew Bezawork-Geleta; Katarina Kluckova; Laurent Chatre; Renata Zobalova; Anna Novakova; Katerina Vanova; Zuzana Ezrova; Ghassan J Maghzal; Silvia Magalhaes Novais; Marie Olsinova; Linda Krobova; Yong Jin An; Eliska Davidova; Zuzana Nahacka; Margarita Sobol; Teresa Cunha-Oliveira; Cristian Sandoval-Acuña; Hynek Strnad; Tongchuan Zhang; Thanh Huynh; Teresa L Serafim; Pavel Hozak; Vilma A Sardao; Werner J H Koopman; Miria Ricchetti; Paulo J Oliveira; Frantisek Kolar; Mikael Kubista; Jaroslav Truksa; Katerina Dvorakova-Hortova; Karel Pacak; Robert Gurlich; Roland Stocker; Yaoqi Zhou; Michael V Berridge; Sunghyouk Park; Lanfeng Dong; Jakub Rohlena; Jiri Neuzil
Journal:  Cell Metab       Date:  2018-11-15       Impact factor: 27.287

Review 6.  Leflunomide, a novel immunomodulator for the treatment of active rheumatoid arthritis.

Authors:  M M Goldenberg
Journal:  Clin Ther       Date:  1999-11       Impact factor: 3.393

7.  PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.

Authors:  Deepti Mathur; Elias Stratikopoulos; Sait Ozturk; Nicole Steinbach; Sarah Pegno; Sarah Schoenfeld; Raymund Yong; Vundavalli V Murty; John M Asara; Lewis C Cantley; Ramon Parsons
Journal:  Cancer Discov       Date:  2017-03-02       Impact factor: 39.397

Review 8.  Animal models of MEN1.

Authors:  Hermine Mohr; Natalia S Pellegata
Journal:  Endocr Relat Cancer       Date:  2017-07-25       Impact factor: 5.678

9.  Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer.

Authors:  Kristin K Brown; Jessica B Spinelli; John M Asara; Alex Toker
Journal:  Cancer Discov       Date:  2017-03-02       Impact factor: 39.397

Review 10.  Current and emerging therapies for PNETs in patients with or without MEN1.

Authors:  Morten Frost; Kate E Lines; Rajesh V Thakker
Journal:  Nat Rev Endocrinol       Date:  2018-02-16       Impact factor: 43.330
  10 in total

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