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Literature DB >> 35167005

Preoperative Radiation for Soft Tissue Sarcomas: How Much Is Needed?

Abstract

OPINION STATEMENT: Preoperative radiation therapy is an important component of curative treatment for extremity and superficial trunk soft tissue sarcomas. It has traditionally been delivered to a dose of 50 Gy in 2 Gy fractions over 5 weeks. With significant advances in the multidisciplinary approach to soft tissue sarcomas, preoperative radiation therapy may be omitted for certain cases, delivered over a shortened period of time (1-3 weeks), deintensified for myxoid liposarcomas, or combined with systemic therapy to improve the therapeutic ratio. This article reviews the innovative preoperative radiation therapy strategies currently used to treat extremity and superficial trunk soft tissue sarcomas.

Entities: Chemical

Keywords: Combination therapy; Dose deintensification; Hypofractionation; Omission of radiation therapy; Preoperative radiation therapy; Soft tissue sarcoma

Mesh：

Year: 2022 PMID： 35167005 DOI： 10.1007/s11864-022-00943-7

Source DB: PubMed Journal: Curr Treat Options Oncol ISSN： 1534-6277

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References

56 in total

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