| Literature DB >> 35166784 |
Anne M Gadermann1,2, Monique Gagné Petteni1,2, Magdalena Janus1,3, Joseph H Puyat2,4, Martin Guhn1, Katholiki Georgiades3.
Abstract
Importance: There remains limited understanding of population-level patterns of mental disorder prevalence for first- and second-generation immigrant and refugee children and youth and how such patterns may vary across mental disorders. Objective: To examine the diagnostic prevalence of conduct, attention-deficit/hyperactivity disorder (ADHD), and mood/anxiety disorders in immigrant, refugee, and nonimmigrant children and youth in British Columbia, Canada. Design, Setting, and Participants: This retrospective, population-level cohort study examined linked health administrative records of children and youth in British Columbia (birth to age 19 years) spanning 2 decades (1996-2016). Physician billings, hospitalizations, and drug dispensations were linked to immigration records to estimate time-in-British Columbia-adjusted prevalence of mental disorder diagnosis among children and youth from immigrant or refugee backgrounds compared with those from nonimmigrant backgrounds. Analyses were conducted from August 2020 to November 2021. Main Outcomes and Measures: The diagnostic prevalence of conduct, ADHD, and mood/anxiety disorders were the main outcomes. Results were stratified by migration category (immigrant, refugee, nonimmigrant), generation status (first- and second-generation), age, and sex.Entities:
Mesh:
Year: 2022 PMID: 35166784 PMCID: PMC8848209 DOI: 10.1001/jamanetworkopen.2021.44934
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Demographic Characteristics of the Study Population
| Characteristic | Study population, No. (%) | |||
|---|---|---|---|---|
| Total (N = 470 464) | Age 3-5 y (n = 335 926) | Age 6-12 y (n = 427 476) | Age 13-19 y (n = 382 282) | |
| Sex | ||||
| Female | 227 217 (48.30) | 162 645 (48.42) | 206 668 (48.35) | 184 882 (48.36) |
| Male | 243 243 (51.70) | 173 279 (51.58) | 220 805 (51.65) | 197 397 (51.64) |
| Generation status | ||||
| First-generation | 86 443 (18.37) | 20 131 (5.99) | 63 054 (14.75) | 75 886 (19.85) |
| Second-generation | 76 119 (16.18) | 66 968 (19.94) | 73 939 (17.30) | 55 372 (14.49) |
| Nonimmigrant | 307 902 (65.45) | 248 827 (74.07) | 290 483 (67.95) | 251 024 (65.66) |
| Migration category | ||||
| Immigrant | 142 011 (87.83) | 74 924 (86.75) | 119 020 (87.41) | 114 987 (88.10) |
| Refugee | 19 686 (12.17) | 11 444 (13.25) | 17 139 (12.59) | 15 539 (11.90) |
Individuals were included in the study population for each age range if they were present in British Columbia for at least 1 of the years within the age range (see Methods section for further details).
A few individuals had missing data for sex.
Identifies migration category for first- and second-generation children. Note that less than 1% arrived under other categorizations and were treated as missing.
Diagnostic Prevalence Estimates of Conduct, ADHD, and Mood/Anxiety Stratified by Age Range, Sex, and Immigration Status, Adjusted for Years in British Columbia
| Subgroup | Prevalence estimate (95% CI), % | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Conduct | ADHD | Mood/anxiety | |||||||
| Age 3-5 y | Age 6-12 y | Age 13-19 y | Age 3-5 y | Age 6-12 y | Age 13-19 y | Age 3-5 y | Age 6-12 y | Age 13-19 y | |
|
| |||||||||
| Overall | 2.88 (2.81-2.94) | 6.22 (6.13-6.30) | 3.25 (3.17-3.32) | 1.16 (1.11-1.22) | 8.22 (8.13-8.32) | 5.69 (5.60-5.79) | 1.73 (1.68-1.78) | 7.82 (7.72-7.91) | 21.12 (21.00-21.31) |
| Female | 1.99 (1.92-2.06) | 3.64 (3.55-3.73) | 2.24 (2.16-2.32) | 0.54 (0.51-0.58) | 4.23 (4.14-4.33) | 3.38 (3.29-3.48) | 1.57 (1.51-1.64) | 6.86 (6.74-6.99) | 25.54 (25.28-25.79) |
| Male | 3.71 (3.61-3.80) | 8.64 (8.50-8.77) | 4.19 (4.08-4.30) | 1.74 (1.66-1.83) | 11.98 (11.82-12.14) | 7.86 (7.71-8.01) | 1.88 (1.81-1.95) | 8.71 (8.58-8.85) | 16.97 (16.76-17.17) |
|
| |||||||||
| First generation | |||||||||
| Overall | 1.53 (1.33-1.76) | 2.72 (2.56-2.90) | 1.16 (1.07-1.26) | 0.82 (0.70-0.97) | 4.30 (4.10-4.51) | 2.13 (2.01-2.25) | 1.62 (1.41-1.86) | 4.78 (4.55-5.01) | 11.07 (10.80-11.36) |
| Female | 1.06 (0.92 (1.22) | 1.37 (1.21-1.55) | 0.80 (0.73-0.87) | 0.39 (0.33-0.46) | 1.73 (1.56-1.92) | 1.07 (0.95-1.19) | 1.47 (1.28-1.69) | 4.16 (3.88-4.47) | 12.83 (12.39-13.28) |
| Male | 1.98 (1.72-2.28) | 3.98 (3.72-4.27) | 1.50 (1.38-1.63) | 1.24 (1.05-1.45) | 6.69 (6.35-7.04) | 3.10 (2.91-3.31) | 1.76 (1.53-2.02) | 5.33 (5.02-5.68) | 9.45 (9.10-9.83) |
| Second generation | |||||||||
| Overall | 2.07 (1.96-2.20) | 4.29 (4.13-4.46) | 2.23 (2.08-2.39) | 0.89 (0.81-0.97) | 5.94 (5.75-6.14) | 3.72 (3.53-3.91) | 1.78 (1.67-1.89) | 5.99 (5.80-6.19) | 15.99 (15.60-16.40) |
| Female | 1.42 (1.33-1.52) | 2.54 (2.41-2.69) | 1.52 (1.41-1.64) | 0.41 (0.37-0.46) | 2.73 (2.54-2.93) | 1.93 (1.74-2.14) | 1.61 (1.50-1.73) | 5.29 (5.02-5.56) | 18.86 (18.25-19.50) |
| Male | 2.66 (2.50-2.82) | 5.95 (5.67-6.23) | 2.86 (2.66-3.07) | 1.32 (1.21-1.45) | 8.81 (8.49-9.14) | 5.30 (5.00-5.61) | 1.93 (1.80-2.06) | 6.62 (6.34-6.91) | 13.45 (12.96-13.97) |
|
| |||||||||
| First generation | |||||||||
| Overall | 2.34 (1.68-3.27) | 4.37 (3.80-5.02) | 1.78 (1.46-2.16) | 0.58 (0.33-1.02) | 4.05 (3.54-4.65) | 2.44 (2.09-2.84) | 2.35 (1.69-3.26) | 6.34 (5.64-7.14) | 16.12 (15.15-17.15) |
| Female | 1.61 (1.15-2.25) | 2.46 (2.07-2.91) | 1.22 (1.00-1.48) | 0.27 (0.15-0.49) | 2.28 (1.96-2.66) | 1.54 (1.29-1.85) | 2.13 (1.53-2.97) | 4.46 (3.75-5.31) | 19.09 (17.27-21.12) |
| Male | 3.01 (2.16-4.20) | 5.75 (4.87-6.79) | 2.30 (1.89-2.79) | 0.86 (0.49-1.51) | 6.21 (5.33-7.22) | 3.49 (2.92-4.17) | 2.55 (1.83-3.54) | 5.71 (4.81-6.78) | 12.54 (11.36-13.85) |
| Second generation | |||||||||
| Overall | 2.26 (1.97-2.60) | 4.22 (3.83-4.64) | 1.72 (1.42-2.09) | 1.05 (0.88-1.27) | 6.20 (5.63-6.57) | 3.67 (3.25-4.14) | 2.58 (2.27-2.94) | 6.49 (6.01-7.02) | 16.91 (15.96-17.92) |
| Female | 1.56 (1.35-1.80) | 2.06 (1.69-2.51) | 1.19 (0.98-1.44) | 0.49 (0.41-0.60) | 2.76 (2.34-3.27) | 2.36 (2.04-2.72) | 2.34 (2.05-2.68) | 5.44 (4.82-6.15) | 21.01 (19.17-23.04) |
| Male | 2.92 (2.53-3.35) | 6.25 (5.61-6.97) | 2.23 (1.85-2.71) | 1.58 (1.31-1.90) | 9.22 (8.45-10.05) | 5.33 (4.64-6.13) | 2.80 (2.46-3.19) | 7.48 (6.77-8.27) | 13.81 (12.61-15.11) |
|
| |||||||||
| Overall | 3.14 (3.07-3.23) | 7.03 (6.93-7.13) | 4.00 (3.89-4.08) | 1.27 (1.21-1.34) | 9.20 (9.08-9.31) | 7.04 (6.91-7.16) | 1.69 (1.64-1.74) | 8.53 (8.42-8.65) | 24.54 (24.34-24.76) |
| Female | 2.18 (2.10-2.26) | 4.17 (4.06-4.28) | 2.74 (2.64-2.85) | 0.60 (0.55-0.64) | 4.89 (4.77-5.01) | 4.27 (4.15-4.40) | 1.54 (1.47-1.61) | 7.46 (7.32-7.62) | 29.76 (29.43-30.06) |
| Male | 4.07 (3.96-4.19) | 9.75 (9.59-9.92) | 5.17(5.03-5.32) | 1.91 (1.82-2.02) | 13.29 (13.11-13.48) | 9.66 (9.47-9.86) | 1.84 (1.76-1.91) | 9.56 (9.39-9.72) | 19.53 (19.28-19.81) |
Abbreviation: ADHD, attention-deficit/hyperactivity disorder.
All prevalence estimates in the table are adjusted by number of years of residence in British Columbia across the full age range. Estimates are based on individual-level data (ie, unique individuals). Overall prevalence estimates (conduct, ADHD, or mood/anxiety), adjusted for years in British Columbia, for the 3-to-5–year, 6-to-12–year, and 13-to-19–year age ranges were 5.29%, 16.07%, and 24.34%, respectively.
Figure. Diagnostic Prevalence Estimates of Conduct, Attention-Deficit/Hyperactivity Disorder (ADHD), Mood/Anxiety Disorders Stratified by Age Range, Sex, and Immigration Status, Adjusted for Years in British Columbia
Estimates are based on individual level data (ie, unique individuals).
Estimated Percentage of Children Diagnosed With Conduct, ADHD, and Mood/Anxiety With at Least 1 Comorbidity, Stratified by Age Range, Sex, and Immigration Status, Adjusted for Years in British Columbia
| Group | Estimated proportion with ≥1 comorbidity, % (95% CI) | ||
|---|---|---|---|
| Age 3-5 y (n = 16 129) | Age 6-12 y (n = 59 958) | Age 13-19 y (n = 71 872) | |
|
| |||
| Overall | 13.62 (13.04-14.19) | 31.27 (30.85-31.69) | 19.26 (18.90-19.63) |
| Female | 9.71 (8.93-10.49) | 23.62 (23.02-24.23) | 13.40 (13.02-13.78) |
| Male | 15.74 (14.99-16.48) | 35.27 (34.74-35.80) | 25.76 (25.20-26.32) |
|
| |||
| First generation | |||
| Overall | 11.35 (8.64-14.07) | 21.87 (20.51-23.23) | 12.30 (11.48-13.11) |
| Female | 8.11 (6.10-10.12) | 16.30 (15.23-17.37) | 8.42 (7.85- 9.00) |
| Male | 13.16 (10.01-16.31) | 24.45 (22.93-25.97) | 16.26 (15.18-17.33) |
| Second generation | |||
| Overall | 11.32 (10.05-12.59) | 24.02 (23.03-25.01) | 14.78 (13.91-15.65) |
| Female | 8.03 (6.98-9.09) | 17.99 (17.15-18.82) | 10.09 (9.47-10.72) |
| Male | 13.03 (11.55-14.51) | 26.97 (25.85-28.09) | 19.48 (18.33-20.62) |
|
| |||
| First generation | |||
| Overall | 7.47 (1.73-13.21) | 18.12 (14.92-21.33) | 9.36 (7.62-11.10) |
| Female | 5.32 (1.23-9.42) | 13.98 (11.50-16.45) | 6.59 (5.37-7.81) |
| Male | 8.64 (2.02-15.25) | 20.96 (17.27-24.65) | 12.72 (10.37-15.07) |
| Second generation | |||
| Overall | 11.06 (8.30-13.82) | 23.39 (21.10-25.68) | 12.83 (10.96-14.71) |
| Female | 7.95 (5.90-10.00) | 17.47 (15.73-19.20) | 8.94 (7.64-10.25) |
| Male | 12.90 (9.67-16.12) | 26.20 (23.65-28.75) | 17.26 (14.76-19.77) |
|
| |||
| Overall | 14.20 (13.55-14.85) | 32.81 (32.34-33.28) | 20.49 (20.08-20.90) |
| Female | 10.13 (9.29-10.96) | 24.79 (24.15-25.44) | 14.29 (13.88-14.71) |
| Male | 16.43 (15.60-17.26) | 37.19 (36.60-37.77) | 27.59 (26.97-28.20) |
Abbreviation: ADHD, attention-deficit/hyperactivity disorder.
Restricted to children with at least 1 mental disorder diagnosis (conduct, ADHD, mood/anxiety) within the age range. All estimates in the table are adjusted to represent presence in British Columbia for the full age range (ie, from 3-5 years, 6-12 years, and 13-19 years, respectively). Comorbidities were restricted to those diagnoses captured in the current study (ie, conduct disorder, ADHD, mood/anxiety disorder).