Literature DB >> 35165859

Cancer Immunoediting: Elimination, Equilibrium, and Immune Escape in Solid Tumors.

Jacek R Wilczyński1, Marek Nowak2,3.   

Abstract

Emphasizing the dynamic processes between cancer and host immune system, the initially discovered concept of cancer immunosurveillance has been replaced by the current concept of cancer immunoediting consisting of three phases: elimination, equilibrium, and escape. Solid tumors composed of both cancer and host stromal cells are an example how the three phases of cancer immunoediting functionally evolve and how tumor shaped by the host immune system gets finally resistant phenotype. The elimination, equilibrium, and escape have been described in this chapter in details, including the role of immune surveillance, cancer dormancy, disruption of the antigen-presenting machinery, tumor-infiltrating immune cells, resistance to apoptosis, as well as the function of tumor stroma, microvesicles, exosomes, and inflammation.
© 2022. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Entities:  

Keywords:  Cancer dormancy; Cancer escape mechanisms; Cancer immunoediting; Immunosurveillance

Mesh:

Year:  2022        PMID: 35165859     DOI: 10.1007/978-3-030-91311-3_1

Source DB:  PubMed          Journal:  Exp Suppl        ISSN: 1664-431X


  295 in total

1.  Anti-apoptosis gene, survivin, and prognosis of neuroblastoma.

Authors:  C Adida; D Berrebi; M Peuchmaur; M Reyes-Mugica; D C Altieri
Journal:  Lancet       Date:  1998-03-21       Impact factor: 79.321

2.  Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis.

Authors:  Ashraf J Abusamra; Zhaohui Zhong; Xiufen Zheng; Mu Li; Thomas E Ichim; Joseph L Chin; Wei-Ping Min
Journal:  Blood Cells Mol Dis       Date:  2005 Sep-Oct       Impact factor: 3.039

Review 3.  Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment.

Authors:  P Allavena; A Mantovani
Journal:  Clin Exp Immunol       Date:  2012-02       Impact factor: 4.330

4.  Existence of autocrine loop between interleukin-6 and transforming growth factor-beta1 in activated rat pancreatic stellate cells.

Authors:  Hiroyoshi Aoki; Hirohide Ohnishi; Kouji Hama; Satoshi Shinozaki; Hiroto Kita; Hironori Yamamoto; Hiroyuki Osawa; Kiichi Sato; Kiichi Tamada; Kentaro Sugano
Journal:  J Cell Biochem       Date:  2006-09-01       Impact factor: 4.429

5.  Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer.

Authors:  Takuya Akashi; Keiichi Koizumi; Koichi Tsuneyama; Ikuo Saiki; Yasuo Takano; Hideki Fuse
Journal:  Cancer Sci       Date:  2008-01-14       Impact factor: 6.716

6.  Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.

Authors:  Yoshinori Abe; Eri Oda-Sato; Kei Tobiume; Keiko Kawauchi; Yoichi Taya; Koji Okamoto; Moshe Oren; Nobuyuki Tanaka
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-21       Impact factor: 11.205

7.  Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells.

Authors:  Khalid Al-Nedawi; Brian Meehan; Johann Micallef; Vladimir Lhotak; Linda May; Abhijit Guha; Janusz Rak
Journal:  Nat Cell Biol       Date:  2008-04-20       Impact factor: 28.824

8.  Identification of interleukin 8 as an inhibitor of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in the ovarian carcinoma cell line OVCAR3.

Authors:  Touraj Abdollahi; Noreen M Robertson; Abbas Abdollahi; Gerald Litwack
Journal:  Cancer Res       Date:  2003-08-01       Impact factor: 12.701

9.  Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

Authors:  Giovanna Andreola; Licia Rivoltini; Chiara Castelli; Veronica Huber; Paola Perego; Paola Deho; Paola Squarcina; Paola Accornero; Francesco Lozupone; Luana Lugini; Annarita Stringaro; Agnese Molinari; Giuseppe Arancia; Massimo Gentile; Giorgio Parmiani; Stefano Fais
Journal:  J Exp Med       Date:  2002-05-20       Impact factor: 14.307

10.  Transcriptional changes induced by the tumor dormancy-associated microRNA-190.

Authors:  Nava Almog; Christine Briggs; Afshin Beheshti; Lili Ma; Kathleen P Wilkie; Edward Rietman; Lynn Hlatky
Journal:  Transcription       Date:  2013-07-01
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  1 in total

1.  The soldiers needed to be awakened: Tumor-infiltrating immune cells.

Authors:  Wang Yaping; Wang Zhe; Chu Zhuling; Li Ruolei; Fan Pengyu; Guo Lili; Ji Cheng; Zhang Bo; Liu Liuyin; Hou Guangdong; Wang Yaoling; Hou Niuniu; Ling Rui
Journal:  Front Genet       Date:  2022-09-29       Impact factor: 4.772

  1 in total

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