Literature DB >> 35165747

Improvement of mortality in severe liver injury after trauma center implementation: a propensity score matched study.

Donghwan Choi1, Junsik Kwon1, Kyoungwon Jung1, Byung Hee Kang2.   

Abstract

PURPOSE: To evaluate changes in the management and outcome of severe liver injury after trauma center implementation.
METHODS: Trauma patients with severe liver injury (organ injury scale score ≥ 4) treated between January 2011 and December 2020 were retrospectively reviewed. A trauma center was built in 2016 at our institution, and patients were dichotomized into two groups: before trauma center (BTC) and after trauma center (ATC) group. Treatment methods and outcomes were compared between the groups with 1:1 propensity score matching.
RESULTS: We included 50 patients in the BTC group and 104 patients in the ATC group. Patients in the ATC group had frequent utilization of angiography (16% vs 47.1%, p < 0.001), faster transfusion [84 (37-152) min vs 17 (10-79) min, p < 0.001], and less fluid administration within 24 h [8.3 (5.7-13.7) L vs 5.7 (3.1-10.1) L, p = 0.002]. However, mortality rate was not significantly different between the groups (26.0% vs 20.2%, p = 0.416). 1:1 propensity score matching was performed using the variables of age, injury severity score, systolic blood pressure, Glasgow Coma Scale, and initial base excess level. After matching, the mortality rate (26.0% vs 10.0%, p = 0.037) and ventilator application (74.0% vs 54.0%, p = 0.037) significantly improved.
CONCLUSION: Severe liver injury management improved after trauma center implementation.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

Entities:  

Keywords:  Liver; Therapeutics; Trauma center; Treatment outcome; Wounds and injuries

Mesh:

Year:  2022        PMID: 35165747     DOI: 10.1007/s00068-022-01909-y

Source DB:  PubMed          Journal:  Eur J Trauma Emerg Surg        ISSN: 1863-9933            Impact factor:   2.374


  2 in total

Review 1.  The current management of hepatic trauma.

Authors:  E H Carrillo; J D Richardson
Journal:  Adv Surg       Date:  2001

2.  Management of severe blunt liver injuries by applying the damage control strategies with packing-oriented surgery: experiences at a single institution in Korea.

Authors:  Kyoungwon Jung; Younghwan Kim; Yunjung Heo; John Cook-Jong Lee; SeokHwa Youn; Jonghwan Moon; Jiyoung Kim; Tea-Youn Kim; Bongwan Kim; Heejung Wang
Journal:  Hepatogastroenterology       Date:  2015 Mar-Apr
  2 in total

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