Literature DB >> 3516467

IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin.

C Genin, B Laurent, J C Sabatier, S Colon, F C Berthoux.   

Abstract

In order to study an experimental model of IgA nephropathy, C3H/HeJ mice which are high IgA responders were strongly immunized orally with ferritin and compared to syngeneic C3H/eB. C3H/HeJ exhibited a significant increase of total IgA level in the serum and of IgA deposits in the mesangium. However the low level of IgA antibody to ferritin detected in the serum and the unsuccessful search for ferritin and antibody to ferritin in the glomeruli suggest that strong oral immunization of C3H/HeJ mice leads to high level of non specific IgA in the serum and deposition of IgA in the kidney.

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Year:  1986        PMID： 3516467      PMCID： PMC1577390     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  37 in total

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Journal:  Digestion       Date:  1973       Impact factor: 3.216

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Journal:  J Immunol       Date:  1970-10       Impact factor: 5.422

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Journal:  Immunochemistry       Date:  1965-09

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Journal:  Immunology       Date:  1970-06       Impact factor: 7.397

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Journal:  Adv Exp Med Biol       Date:  1978       Impact factor: 2.622

6.  Immunoglobulin A glomerulonephritis: a clinicopathologic study.

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Journal:  Lab Invest       Date:  1975-02       Impact factor: 5.662

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Journal:  Lab Invest       Date:  1975-06       Impact factor: 5.662

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Journal:  Clin Nephrol       Date:  1977-11       Impact factor: 0.975

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Authors:  J C Sabatier; C Genin; H Assenat; S Colon; F Ducret; F C Berthoux
Journal:  Clin Nephrol       Date:  1979-01       Impact factor: 0.975

10.  Improvements in epoxy resin embedding methods.

Authors:  J H LUFT
Journal:  J Biophys Biochem Cytol       Date:  1961-02
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  5 in total

1.  IgA-containing immune complexes after challenge with food antigens in patients with IgA nephropathy.

Authors:  S Jackson; Z Moldoveanu; K A Kirk; B A Julian; T F Patterson; A L Mullins; T Jilling; J Mestecky; J H Galla
Journal:  Clin Exp Immunol       Date:  1992-08       Impact factor: 4.330

2.  Detection and characterization of circulating and glomerular immune complexes in experimental IgA nephropathy.

Authors:  J González-Cabrero; J Egido; A Barat; E González
Journal:  Immunology       Date:  1990-07       Impact factor: 7.397

3.  Defective hepatic handling of IgA immune aggregates by mice with experimental IgA nephropathy.

Authors:  E González; J González-Cabrero; J Egido
Journal:  Immunology       Date:  1989-07       Impact factor: 7.397

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Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

Review 5.  Immunopathogenesis of experimental IgA nephropathy.

Authors:  A Rifai
Journal:  Springer Semin Immunopathol       Date:  1994
  5 in total

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