Literature DB >> 3516395

Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous leukemia in relapse: a Leukemia Intergroup Study.

W R Vogler, H D Preisler, E F Winton, A J Gottlieb, J Goldberg, J Brennan, H Grunwald, K Rai, G Browman, K B Miller.   

Abstract

Patients with acute myelogenous leukemia in relapse who were ineligible for further anthracycline therapy either because they were judged to be anthracycline resistant or had received the maximum doses were randomized to receive high-dose cytarabine (3 g/m2 every 12 hours for 6 days) or amsacrine (75 mg/m2 daily for 7 days). The response rates in both groups were similar: three of 25 patients given high-dose cytarabine and three of 23 given amsacrine obtained complete remissions.

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Year:  1986        PMID: 3516395

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  6 in total

Review 1.  Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens.

Authors:  W Hiddemann
Journal:  Ann Hematol       Date:  1991-04       Impact factor: 3.673

Review 2.  The toxicity of cytarabine.

Authors:  J Stentoft
Journal:  Drug Saf       Date:  1990 Jan-Feb       Impact factor: 5.606

Review 3.  Treatment strategies in acute myeloid leukemia (AML). B. Second line treatment.

Authors:  W Hiddemann; T Büchner
Journal:  Blut       Date:  1990-03

4.  High-dose ara-C and etoposide in refractory or relapsing acute leukemia.

Authors:  M Freund; H Link; H Diedrich; S LeBlanc; H J Wilke; H Poliwoda
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

5.  Five-day 4'-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia.

Authors:  M Freund; S Giller; F Hinrichs; A Baars; J Meran; A Körfer; H Link; H Poliwoda
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

6.  Efficacy of mouth rinse in preventing oral mucositis in patients receiving high-dose cytarabine for allogeneic hematopoietic stem cell transplantation.

Authors:  Takehiko Mori; Kaori Hasegawa; Ai Okabe; Natsuki Tsujimura; Yusuke Kawata; Tomoko Yashima; Naoko Kobayashi; Sakiko Kondo; Yoshinobu Aisa; Jun Kato; Kazuyuki Tsunoda; Tetsuo Nagai; Taneaki Nakagawa; Naoyuki Shigematsu; Atsushi Kubo; Yasuo Ikeda; Shinichiro Okamoto
Journal:  Int J Hematol       Date:  2008-10-30       Impact factor: 2.490

  6 in total

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