Literature DB >> 35155140

Development of a Minimally Invasive and Non-invasive Lipolysis Laser System for Effective Fat Reduction.

Ji-Young Lee1, Seok-Won Oh1, Han-Young Ryu1, Young-Seok Seo1.   

Abstract

Introduction: Obesity is a global problem because it causes various complications. Methods for reducing fat for healthy life are being studied. In this study, we developed a minimally invasive and non-invasive lipolysis laser system for effective fat reduction.
Methods: The laser had the wavelengths of 1980 nm and 2300 nm which have very good absorption of fat and water. We developed a minimally invasive laser system that breaks down fat by direct irradiation of fat tissue. This minimally invasive laser system uses a 808 nm diode laser and Nd:YVO4 to generate the 1064 nm wavelength, which is the pumping source of the nonlinear crystals. It is a mid-infrared lipolysis laser system having two wavelengths of 1980 nm and 2300 nm by controlling the temperature of nonlinear crystals. We also developed a non-invasive laser system that reduces fat with hyperthermia treatment by raising the temperature of adipocytes with a 1060 nm penetrating depth into the skin. In this non-invasive laser system, the In gallium arsenide (GaAs) diode laser is irradiated on the skin with an area of 4 × 8 cm2 through the hand-piece. The cooling system in the hand-piece protects the skin from burns. We studied the effectiveness and safety of each system through animal experiment. We studied the effects of lipolysis when these two systems were combined.
Results: This research uses new wavelengths (1980 nm, 2300 nm) to increase the fat reduction effect with low energy (1.3 W). After using the 1060 nm (1.1 W/cm2) wavelength laser, when the 1980 nm and 2300 nm (1.3 W) laser were used, a lipolysis effect of about 35 % was obtained.
Conclusion: We have developed a 1.3 W mid-infrared (1980 nm, 2300 nm) laser with good lipolysis effect with low power.
Copyright © 2021 J Lasers Med Sci.

Entities:  

Keywords:  Laser lipolysis; Low energy laser; Mid-infrared; Nonlinear crystal

Year:  2021        PMID: 35155140      PMCID: PMC8837834          DOI: 10.34172/jlms.2021.55

Source DB:  PubMed          Journal:  J Lasers Med Sci        ISSN: 2008-9783


  15 in total

1.  Laser lipolysis: flaccidity under control.

Authors:  Ana Zulmira Diniz Badin; Lea Mara Moraes; Luciana Gondek; Marlon Gouveia Chiaratti; Luigi Canta
Journal:  Aesthetic Plast Surg       Date:  2002 Sep-Oct       Impact factor: 2.326

2.  Ablative targeting of fatty-tissue using a high-powered diode laser.

Authors:  Dan mon O'Dey; Andreas Prescher; Reinhart Poprawe; Sebastian Gaus; Sven Stanzel; Norbert Pallua
Journal:  Lasers Surg Med       Date:  2008-02       Impact factor: 4.025

Review 3.  Body contouring using 635-nm low level laser therapy.

Authors:  Mark S Nestor; Jessica Newburger; Matthew B Zarraga
Journal:  Semin Cutan Med Surg       Date:  2013-03

4.  Laser lipolysis: an update.

Authors:  Jason C McBean; Bruce E Katz
Journal:  J Clin Aesthet Dermatol       Date:  2011-07

5.  Subcutaneous adipose tissue response to a non-invasive hyperthermic treatment using a 1,060 nm laser.

Authors:  John W Decorato; Bo Chen; Rafael Sierra
Journal:  Lasers Surg Med       Date:  2017-01-19       Impact factor: 4.025

Review 6.  1060 nm Diode Hyperthermic Laser Lipolysis:The Latest in Non-Invasive Body Contouring.

Authors:  Laura Schilling; Nazanin Saedi; Robert Weiss
Journal:  J Drugs Dermatol       Date:  2017-01-01       Impact factor: 2.114

7.  Safety and Efficacy of a Noninvasive 1,060-nm Diode Laser for Fat Reduction of the Flanks.

Authors:  Bruce Katz; Sean Doherty
Journal:  Dermatol Surg       Date:  2018-03       Impact factor: 3.398

8.  Hyperthermic injury to adipocyte cells by selective heating of subcutaneous fat with a novel radiofrequency device: feasibility studies.

Authors:  Walfre Franco; Amogh Kothare; Stephen J Ronan; Roy C Grekin; Timothy H McCalmont
Journal:  Lasers Surg Med       Date:  2010-07       Impact factor: 4.025

9.  Laser-assisted Lipolysis Burn Safety: Proposed Detailed Parameters with Assessment of Their Efficacy and Safety.

Authors:  Yasser Helmy Ali
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-10-03

10.  Enhanced Tissue Ablation Efficiency with a Mid-Infrared Nonlinear Frequency Conversion Laser System and Tissue Interaction Monitoring Using Optical Coherence Tomography.

Authors:  Bongkyun Kim; Dae Yu Kim
Journal:  Sensors (Basel)       Date:  2016-04-26       Impact factor: 3.576

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