Literature DB >> 35153308

Influence of low-level gelling agents on the dissolution and in-vitro nutrient release study of coconut water-based hydrogel.

Eng-Keng Seow1, Vikneswaran Muthu2, Ahmad Munir Che Muhamed3, Cheong Hwa Ooi3, Rabindarjeet Singh3, Azhar Mat Easa2, Thuan-Chew Tan2.   

Abstract

The purpose of this study was to evaluate the controlled-release properties of nutrients from coconut water-based hydrogel. Hydrogels were prepared at varying proportions of gellan and xanthan gums such that the total weight of the gelling agents for all 11 formulations was 1% (w/w) in coconut water. The formulation of the hydrogel was selected using gravimetric analysis by evaluating the dissolution weight of the hydrogel in simulated gastric fluid and simulated intestinal fluid. Interestingly, hydrogel with 0.7% gellan gum and 0.3% xanthan gum showed the most tolerance towards simulated gastric and intestinal fluids over a 1-h period. The in-vitro release study was performed in simulated gastric fluid and followed by simulated intestinal fluid for about 2 h. The trend of release profile showed that the hydrogel had the ability to sustain the nutrients release over a period of 1 h. After 75 min, the release trend was static indicated the nutrients was released from the hydrogel. In conclusion, a coconut water-based hydrogel formulated with 0.7% of gellan and 0.3% of xanthan gum has demonstrated its controlled-release property as evidenced by its effectiveness in the sustained release of nutrients over a period of 1 h. © Association of Food Scientists & Technologists (India) 2021.

Entities:  

Keywords:  Coconut water; Controlled-release; Gellan; Hydrogel; In-vitro; Xanthan

Year:  2021        PMID: 35153308      PMCID: PMC8814071          DOI: 10.1007/s13197-021-05045-0

Source DB:  PubMed          Journal:  J Food Sci Technol        ISSN: 0022-1155            Impact factor:   2.701


  11 in total

1.  Rehydration after exercise with fresh young coconut water, carbohydrate-electrolyte beverage and plain water.

Authors:  Mohamed Saat; Rabindarjeet Singh; Roland Gamini Sirisinghe; Mohd Nawawi
Journal:  J Physiol Anthropol Appl Human Sci       Date:  2002-03

2.  Improved understanding of human anatomy through self-guided radiological anatomy modules.

Authors:  Andrew W Phillips; Sandy G Smith; Callum F Ross; Christopher M Straus
Journal:  Acad Radiol       Date:  2012-04-24       Impact factor: 3.173

3.  Composition, physicochemical properties and thermal inactivation kinetics of polyphenol oxidase and peroxidase from coconut (Cocos nucifera) water obtained from immature, mature and overly-mature coconut.

Authors:  Thuan-Chew Tan; Lai-Hoong Cheng; Rajeev Bhat; Gulam Rusul; Azhar Mat Easa
Journal:  Food Chem       Date:  2013-07-16       Impact factor: 7.514

4.  Beads made of cyclodextrin and oil for the oral delivery of lipophilic drugs: in vitro studies in simulated gastro-intestinal fluids.

Authors:  M Hamoudi; E Fattal; C Gueutin; V Nicolas; A Bochot
Journal:  Int J Pharm       Date:  2011-02-16       Impact factor: 5.875

5.  The intravenous use of coconut water.

Authors:  D Campbell-Falck; T Thomas; T M Falck; N Tutuo; K Clem
Journal:  Am J Emerg Med       Date:  2000-01       Impact factor: 2.469

6.  Chitosan in situ gelation for improved drug loading and retention in poloxamer 407 gels.

Authors:  Tofeeq Ur-Rehman; Staffan Tavelin; Gerhard Gröbner
Journal:  Int J Pharm       Date:  2011-02-16       Impact factor: 5.875

Review 7.  An insight into the emerging exopolysaccharide gellan gum as a novel polymer.

Authors:  Vipul D Prajapati; Girish K Jani; Bhumi S Zala; Tohra A Khutliwala
Journal:  Carbohydr Polym       Date:  2013-01-21       Impact factor: 9.381

8.  Rehydration with sodium-enriched coconut water after exercise-induced dehydration.

Authors:  I Ismail; R Singh; R G Sirisinghe
Journal:  Southeast Asian J Trop Med Public Health       Date:  2007-07       Impact factor: 0.267

9.  Self-structuring foods based on acid-sensitive low and high acyl mixed gellan systems to impact on satiety.

Authors:  Jennifer F Bradbeer; Robin Hancocks; Fotios Spyropoulos; Ian T Norton
Journal:  Food Hydrocoll       Date:  2014-03       Impact factor: 9.147

Review 10.  The chemical composition and biological properties of coconut (Cocos nucifera L.) water.

Authors:  Jean W H Yong; Liya Ge; Yan Fei Ng; Swee Ngin Tan
Journal:  Molecules       Date:  2009-12-09       Impact factor: 4.411

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