Lucía Serrano González1,2, Tirso Pérez-Medina3, Beatriz Bueno Olalla4, Ana Royuela5, María de Los Reyes De La Cuesta3, David Saéz de la Mata4, Esther Domínguez-Franjo6, Laura Calles-Sastre3, Virginia Engels3. 1. Department of Gynaecology and Obstetrics, Puerta de Hierro Majadahonda University Hospital, Joaquín Rodrigo St, 1, 28222, Majadahonda, Madrid, Spain. luciaserranogon@gmail.com. 2. Department of Gynaecology and Obstetrics, Hospital Universitario Ramón y Cajal, M-607, km. 9, 100, 28034, Madrid, Madrid, Spain. luciaserranogon@gmail.com. 3. Department of Gynaecology and Obstetrics, Puerta de Hierro Majadahonda University Hospital, Joaquín Rodrigo St, 1, 28222, Majadahonda, Madrid, Spain. 4. Department of Gynaecology and Obstetrics, Infanta Sofía University Hospital, Paseo de Europa, 34, 28703, San Sebastián de los Reyes, Madrid, Spain. 5. Biostatistics Unit, Biomedical Research Institute Puerta de Hierro-Segovia de Arana (CIBERESP) ES, Joaquín Rodrigo St, 1, 28222, Majadahonda, Madrid, Spain. 6. Department of Radio Diagnosis, Infanta Sofía University Hospital, Paseo de Europa, 34, 28703, San Sebastián de los Reyes, Madrid, Spain.
Abstract
BACKGROUND: In 60% of sterile couples a female factor is present, with these being tubal factors in 30-50% of cases. A tubal patency test is also required in women without a male partner undergoing fertility treatment. Thus, an accurate, safe and tolerable technique should be available. The aim of this study is to determine and to compare hysterosalpingo-foam sonography (HyFoSy) and hysterosalpingography (HSG) tolerability in terms of pain and anxiety. METHODS: This is a prospective real-world setting multicentre study conducted in two tertiary hospitals in Madrid. 210 infertile women/women without a male partner looking to get pregnant were recruited; 111 for the HyFoSy group and 99 for the HSG group. Tolerability was measured in terms of anxiety by the State Trait Anxiety Inventory (STAI) and pain by the Visual Analogue Scale (VAS). RESULTS: Median VAS score in HyFoSy group was 2 (P25; P75: 1; 3) versus 5 (4; 8) in HSG group, p < 0.001. The median State-STAI score in the HSG group was 18 points (10; 26) versus 10 (7; 16) in the HyFoSy group (p < 0.001); the median Trait-STAI score in the HSG group was 15 (11; 21) versus 13 (9; 17) in the HyFoSy group (p = 0.044). CONCLUSIONS: HyFoSy shows higher tolerability to both: pain and anxiety. It is related to less pain and less post-test anxiety than HSG.
BACKGROUND: In 60% of sterile couples a female factor is present, with these being tubal factors in 30-50% of cases. A tubal patency test is also required in women without a male partner undergoing fertility treatment. Thus, an accurate, safe and tolerable technique should be available. The aim of this study is to determine and to compare hysterosalpingo-foam sonography (HyFoSy) and hysterosalpingography (HSG) tolerability in terms of pain and anxiety. METHODS: This is a prospective real-world setting multicentre study conducted in two tertiary hospitals in Madrid. 210 infertile women/women without a male partner looking to get pregnant were recruited; 111 for the HyFoSy group and 99 for the HSG group. Tolerability was measured in terms of anxiety by the State Trait Anxiety Inventory (STAI) and pain by the Visual Analogue Scale (VAS). RESULTS: Median VAS score in HyFoSy group was 2 (P25; P75: 1; 3) versus 5 (4; 8) in HSG group, p < 0.001. The median State-STAI score in the HSG group was 18 points (10; 26) versus 10 (7; 16) in the HyFoSy group (p < 0.001); the median Trait-STAI score in the HSG group was 15 (11; 21) versus 13 (9; 17) in the HyFoSy group (p = 0.044). CONCLUSIONS: HyFoSy shows higher tolerability to both: pain and anxiety. It is related to less pain and less post-test anxiety than HSG.