Literature DB >> 3515097

An essential fungal growth factor derived from ergosterol: a new end product of sterol biosynthesis in fungi?

L W Parks, R J Rodriguez, C Low.   

Abstract

Concentrations of ergosterol as low as 1.2 mM are effective in satisfying the essential high specificity microrequirement for C5,6 unsaturated sterol in yeast. In a sterol auxotroph supplemented with saturated sterol (cholestanol), aqueous extracts of yeast provide a growth factor that eliminates the ergosterol microrequirement. The factor is easily differentiated from ergosterol by solubility, thermostability, and thin layer and liquid chromatography and is functional at levels equivalent to those of vitamins, hormones and pheromones.

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Year:  1986        PMID： 3515097     DOI： 10.1007/bf02534308

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  7 in total

1.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

2.  Identification and properties of a sterol-binding polysaccharide isolated from Saccharomyces cerevisiae.

Authors:  E D Thompson; B A Knights; L W Parks
Journal:  Biochim Biophys Acta       Date:  1973-03-30

3.  Isolation from yeast of a metabolically active water-soluble form of ergosterol.

Authors:  B G Adams; L W Parks
Journal:  J Lipid Res       Date:  1968-01       Impact factor: 5.922

4.  Yeast sterol esters and their relationship to the growth of yeast.

Authors:  R B Bailey; L W Parks
Journal:  J Bacteriol       Date:  1975-11       Impact factor: 3.490

5.  A requirement for ergosterol to permit growth of yeast sterol auxotrophs on cholestanol.

Authors:  R J Rodriguez; F R Taylor; L W Parks
Journal:  Biochem Biophys Res Commun       Date:  1982-05-31       Impact factor: 3.575

6.  Application of high-performance liquid chromatographic separation of free sterols to the screening of yeast sterol mutants.

Authors:  R J Rodriguez; L W Parks
Journal:  Anal Biochem       Date:  1982-01-01       Impact factor: 3.365

7.  Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs.

Authors:  R J Rodriguez; L W Parks
Journal:  Arch Biochem Biophys       Date:  1983-09       Impact factor: 4.013
  7 in total
  3 in total

1.  Ergosterol-to-Biomass Conversion Factors for Aquatic Hyphomycetes.

Authors:  M O Gessner; E Chauvet
Journal:  Appl Environ Microbiol       Date:  1993-02       Impact factor: 4.792

2.  Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase.

Authors:  E J Corey; S P Matsuda; B Bartel
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205

3.  Structural discrimination in the sparking function of sterols in the yeast Saccharomyces cerevisiae.

Authors:  R T Lorenz; W M Casey; L W Parks
Journal:  J Bacteriol       Date:  1989-11       Impact factor: 3.490
  3 in total

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