Audrey C Leasure1, Jeffrey M Cohen2. 1. Yale School of Medicine, New Haven, CT, USA. 2. Department of Dermatology, Yale School of Medicine, 15 York Street, New Haven, CT, USA. jeffrey.m.cohen@yale.edu.
Abstract
INTRODUCTION: Eczema is a cause of significant morbidity in the US but few estimates of eczema prevalence in racially and ethnically diverse adult cohorts exist. METHODS: We performed a cross-sectional analysis of All of Us. Eczema cases were identified in EHR data using ICD-9-CM 691, 691.8 and 705.8; ICD-10-CM L20, L20.8, L20.9, L30 and L30.1; and SNOMED codes 24079001 and 43116000. We calculated the prevalence of eczema and 95% confidence intervals (CI) among participants across age and self-identified racial and ethnic groups using the Wald method. RESULTS: Of 203,813 All of Us participants with available EHR data (average age 55 years, standard deviation [SD] 17; 63% female), we identified 11,244 eczema cases with an average age of 59 years (SD 16) and a 2:1 female predominance (68% female).The prevalence of eczema increased with age, ranging from 3.6% (95% CI 3.4-3.8) in those age 18 to 34 to 8.3% (95% CI 8.0-8.7) in those age 75 and older. The prevalence of eczema also varied by race and ethnicity: eczema prevalence was significantly higher in Asian and white participants (6.5% [95% CI 5.9-7.2] and 6.2% [95% CI 6.1-6.4], respectively) compared to Black and Hispanic participants (5.1% [95% CI 4.9-5.3] and 4.1% [3.9-4.3], respectively) (all pairwise comparisons p < 0.001). CONCLUSION: In the All of Us study, the prevalence of eczema among US adults was 5.4-5.6% and varied by age and race/ethnicity.
INTRODUCTION: Eczema is a cause of significant morbidity in the US but few estimates of eczema prevalence in racially and ethnically diverse adult cohorts exist. METHODS: We performed a cross-sectional analysis of All of Us. Eczema cases were identified in EHR data using ICD-9-CM 691, 691.8 and 705.8; ICD-10-CM L20, L20.8, L20.9, L30 and L30.1; and SNOMED codes 24079001 and 43116000. We calculated the prevalence of eczema and 95% confidence intervals (CI) among participants across age and self-identified racial and ethnic groups using the Wald method. RESULTS: Of 203,813 All of Us participants with available EHR data (average age 55 years, standard deviation [SD] 17; 63% female), we identified 11,244 eczema cases with an average age of 59 years (SD 16) and a 2:1 female predominance (68% female).The prevalence of eczema increased with age, ranging from 3.6% (95% CI 3.4-3.8) in those age 18 to 34 to 8.3% (95% CI 8.0-8.7) in those age 75 and older. The prevalence of eczema also varied by race and ethnicity: eczema prevalence was significantly higher in Asian and white participants (6.5% [95% CI 5.9-7.2] and 6.2% [95% CI 6.1-6.4], respectively) compared to Black and Hispanic participants (5.1% [95% CI 4.9-5.3] and 4.1% [3.9-4.3], respectively) (all pairwise comparisons p < 0.001). CONCLUSION: In the All of Us study, the prevalence of eczema among US adults was 5.4-5.6% and varied by age and race/ethnicity.
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