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Literature DB >> 3514663

Proteolytic activity of a clinical isolate of Cryptococcus neoformans.

Abstract

A clinical isolate of Cryptococcus neoformans was grown on essential salts medium without (NH4)2SO4 and supplemented with bovine serum albumin as the sole carbon and nitrogen source. Growth on this medium resulted in secretion of proteolytic enzymes by the organism. The secretion of protease enzymes was inhibited by (NH4)2SO4 and glucose. Proteolytic activity may be a factor in virulence and pathogenicity of C. neoformans.

Entities: Chemical Species

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Year: 1986 PMID： 3514663 PMCID： PMC268711 DOI： 10.1128/jcm.23.3.631-633.1986

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

12 in total

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Authors: H E Müller; K K Sethi
Journal: Med Microbiol Immunol Date: 1972 Impact factor: 3.402

2. Secretion of acid proteinases by different species of the genus Candida.

Authors: R Rüchel; K Uhlemann; B Böning
Journal: Zentralbl Bakteriol Mikrobiol Hyg A Date: 1983-11

3. Alkaline protease from Neurospora crassa. Purification and partial characterization.

Authors: R A Lindberg; L D Eirich; J S Price; L Wolfinbarger; H Drucker
Journal: J Biol Chem Date: 1981-01-25 Impact factor: 5.157

4. A variety of Candida proteinases and their possible targets of proteolytic attack in the host.

Authors: R Rüchel
Journal: Zentralbl Bakteriol Mikrobiol Hyg A Date: 1984-07

5. Cryptococcus neoformans. 3. Inhibition of phagocytosis.

Authors: G S Bulmer; M D Sans
Journal: J Bacteriol Date: 1968-01 Impact factor: 3.490

6. Regulation of exocellular proteases in Neurospora crassa: induction and repression of enzyme synthesis.

Authors: H Drucker
Journal: J Bacteriol Date: 1972-06 Impact factor: 3.490

7. Pathogenicity of anaerobic gram-negative rods: possible mechanisms.

Authors: T Hofstad
Journal: Rev Infect Dis Date: 1984 Mar-Apr

8. Purification and partial characterization of a Nocardia brasiliensis extracellular protease.

Authors: H Zlotnik; V L Schramm; H R Buckley
Journal: J Bacteriol Date: 1984-02 Impact factor: 3.490

9. Phenoloxidase activity and virulence in isogenic strains of Cryptococcus neoformans.

Authors: J C Rhodes; I Polacheck; K J Kwon-Chung
Journal: Infect Immun Date: 1982-06 Impact factor: 3.441

10. Extracellular acid proteases from Neurospora crassa.

Authors: R A Lindberg; W G Rhodes; L D Eirich; H Drucker
Journal: J Bacteriol Date: 1982-06 Impact factor: 3.490

18 in total

1. Variants of a Cryptococcus neoformans strain elicit different inflammatory responses in mice.

Authors: L C Chen; A Casadevall
Journal: Clin Diagn Lab Immunol Date: 1999-03

2. Purification and characterization of a 43-kilodalton extracellular serine proteinase from Cryptococcus neoformans.

Authors: Jae il Yoo Ji; Yeong Seon Lee; Chul-Yong Song; Bong Su Kim
Journal: J Clin Microbiol Date: 2004-02 Impact factor: 5.948

Review 3. Antibody immunity and invasive fungal infections.

Authors: A Casadevall
Journal: Infect Immun Date: 1995-11 Impact factor: 3.441

4. Extracellular proteolytic enzyme activity of Histoplasma capsulatum var. duboisii.

Authors: F A Muotoe-Okafor; H C Gugnani; O O Obidoa
Journal: Mycopathologia Date: 1996 Impact factor: 2.574

5. Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis.

Authors: R T Nelson; J Hua; B Pryor; J K Lodge
Journal: Genetics Date: 2001-03 Impact factor: 4.562