| Literature DB >> 3514459 |
W A Siddiqui, L Q Tam, S C Kan, K J Kramer, S E Case, K L Palmer, K M Yamaga, G S Hui.
Abstract
Monoclonal antibodies to the major Plasmodium falciparum merozoite surface coat and rhoptry antigens were produced. A combination of the affinity-purified polypeptides with Freund complete adjuvant which was given three times completely protected an Aotus lemurinus azure (karotype VI) monkey against homologous challenge; however, immunization with the same polypeptides with a muramyl dipeptide derivative [MDP-Lys(L18)] did not protect a second Aotus monkey, even though comparable high antibody titers were induced.Entities:
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Year: 1986 PMID: 3514459 PMCID: PMC262236 DOI: 10.1128/iai.52.1.314-318.1986
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441