| Literature DB >> 351422 |
G F Gauthier, S Lowey, A W Hobbs.
Abstract
Slow and fast isoenzymes of myosin coexist in all the fibres of a fast-twitch mammalian muscle during early development. They later become segregated into different populations of fibres. Slow myosin is most abundant when the speed of contraction of the muscle is slow and the fibres are multiply innervated; its synthesis in the majority of the fibres seems to be 'switched off' when the speed of contraction increases and the fibres become innervated by single motoneurones.Entities:
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Year: 1978 PMID: 351422 DOI: 10.1038/274025a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962