Erna Davidović Cvetko1, Nebojša Nešić1, Anita Matić2,3, Jasminka Milas Ahić4,5, Ines Drenjančević6,7. 1. Health Studies Department, College of Applied Sciences Lavoslav Ruzicka in Vukovar, Županijska 50, 32000, Vukovar, Croatia. 2. Department of Physiology and Immunology, Faculty of Medicine Osijek, University of Josip Juraj Strossmayer Osijek, J. Huttlera 4, 31000, Osijek, Croatia. 3. Scientific Centre of Excellence for Personalized Health Care, University of Josip Juraj Strossmayer Osijek, Trg Svetog Trojstva 3, 31000, Osijek, Croatia. 4. Department of Pathophysiology, Faculty of Medicine Osijek, University of Josip Juraj Strossmayer Osijek, J. Huttlera 4, 31000, Osijek, Croatia. 5. Department of Internal Medicine, Clinical Hospital Centre Osijek, J. Huttlera 4, 31000, Osijek, Croatia. 6. Department of Physiology and Immunology, Faculty of Medicine Osijek, University of Josip Juraj Strossmayer Osijek, J. Huttlera 4, 31000, Osijek, Croatia. ines.drenjancevic@mefos.hr. 7. Scientific Centre of Excellence for Personalized Health Care, University of Josip Juraj Strossmayer Osijek, Trg Svetog Trojstva 3, 31000, Osijek, Croatia. ines.drenjancevic@mefos.hr.
Abstract
PURPOSE: The effects of aerobic exercise on bone metabolism are still unclear. Thus, the main goal of this study was to explore if there was an effect of the short-term aerobic exercise program on the bone remodeling process and if there were sex differences in the effect of the training program on bone metabolism. METHODS: Twenty-one participants (men and women) aged 20-23 performed an 8-week aerobic exercise program three times per week in 1-h sessions with increases in the exercise load every 2 weeks. Bone density, bone mineral content and concentration of markers of bone metabolism: osteocalcin, C-terminal procollagen type I peptide, pyridinoline, parathyroid hormone, osteoprotegerin, and the receptor activator of nuclear kappa B ligand by ELISA were measured at the start and at the end of the study, while changes in body composition were assessed by a bioelectric impedance analysis method 6 times during the study. RESULTS: The aerobic exercise program increased the concentration of osteocalcin (11.34 vs 14.24 ng/ml), pyridinoline (67.51 vs 73.99 nmol/l), and the receptor activator of nuclear kappa B ligand (95.122 vs 158.15 pg/ml). A statistically significant increase in bone density at neck mean (1.122 vs 1.176 g/cm3) and in bone mineral content at dual femur (33.485 vs 33.700 g) was found in women, while there was no statistically significant change at any site in men. CONCLUSION: 8 weeks of the aerobic exercise program with increment in intensity increased some of bone remodeling biomarkers and showed different effects for men and women.
PURPOSE: The effects of aerobic exercise on bone metabolism are still unclear. Thus, the main goal of this study was to explore if there was an effect of the short-term aerobic exercise program on the bone remodeling process and if there were sex differences in the effect of the training program on bone metabolism. METHODS: Twenty-one participants (men and women) aged 20-23 performed an 8-week aerobic exercise program three times per week in 1-h sessions with increases in the exercise load every 2 weeks. Bone density, bone mineral content and concentration of markers of bone metabolism: osteocalcin, C-terminal procollagen type I peptide, pyridinoline, parathyroid hormone, osteoprotegerin, and the receptor activator of nuclear kappa B ligand by ELISA were measured at the start and at the end of the study, while changes in body composition were assessed by a bioelectric impedance analysis method 6 times during the study. RESULTS: The aerobic exercise program increased the concentration of osteocalcin (11.34 vs 14.24 ng/ml), pyridinoline (67.51 vs 73.99 nmol/l), and the receptor activator of nuclear kappa B ligand (95.122 vs 158.15 pg/ml). A statistically significant increase in bone density at neck mean (1.122 vs 1.176 g/cm3) and in bone mineral content at dual femur (33.485 vs 33.700 g) was found in women, while there was no statistically significant change at any site in men. CONCLUSION: 8 weeks of the aerobic exercise program with increment in intensity increased some of bone remodeling biomarkers and showed different effects for men and women.
Authors: Robert H Coker; Rick H Williams; Patrick M Kortebein; Dennis H Sullivan; William J Evans Journal: Metab Syndr Relat Disord Date: 2009-08 Impact factor: 1.894
Authors: Eimear Dolan; Ian Varley; Kathryn E Ackerman; Rosa Maria R Pereira; Kirsty Jayne Elliott-Sale; Craig Sale Journal: Exerc Sport Sci Rev Date: 2020-04 Impact factor: 6.230