Literature DB >> 351413

Chemotherapy of parasite infections.

H Van den Bossche.   

Abstract

Although several good antiparasitic agents are available, new drugs are needed for the treatment of diseases such as chloroquine-resistant malaria, Chagas' disease, leishmaniasis and filariasis. The 'semirational approach' should be the basis for their synthesis.

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Year:  1978        PMID： 351413     DOI： 10.1038/273626a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  5 in total

1.  Synthesis of macrocyclic trypanosomal cysteine protease inhibitors.

Authors:  Yen Ting Chen; Ricardo Lira; Elizabeth Hansell; James H McKerrow; William R Roush
Journal:  Bioorg Med Chem Lett       Date:  2008-06-10       Impact factor: 2.823

2.  [Effect of the anthelminthic levamisole on the first-stage larva of Angiostrongylus cantonensis in infected rats].

Authors:  A Ishih
Journal:  Parasitol Res       Date:  1994       Impact factor: 2.289

3.  In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

Authors:  Yen Ting Chen; Linda S Brinen; Iain D Kerr; Elizabeth Hansell; Patricia S Doyle; James H McKerrow; William R Roush
Journal:  PLoS Negl Trop Dis       Date:  2010-09-14

4.  Mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis.

Authors:  S N Moreno; R Docampo
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031

5.  Pharmacophore modeling for anti-Chagas drug design using the fragment molecular orbital method.

Authors:  Ryunosuke Yoshino; Nobuaki Yasuo; Daniel Ken Inaoka; Yohsuke Hagiwara; Kazuki Ohno; Masaya Orita; Masayuki Inoue; Tomoo Shiba; Shigeharu Harada; Teruki Honma; Emmanuel Oluwadare Balogun; Josmar Rodrigues da Rocha; Carlos Alberto Montanari; Kiyoshi Kita; Masakazu Sekijima
Journal:  PLoS One       Date:  2015-05-11       Impact factor: 3.240
  5 in total

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