Literature DB >> 35140368

Unwinding the mutational signatures of a DNA topoisomerase enzyme.

Ammal Abbasi, Ludmil B Alexandrov.   

Abstract

Entities:  

Keywords:  Cancer; Molecular biology

Mesh：

Substances：

Year:  2022        PMID： 35140368     DOI： 10.1038/d41586-022-00301-5

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

1.  Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.

Authors:  Ian G Cowell; Zbyslaw Sondka; Kayleigh Smith; Ka Cheong Lee; Catriona M Manville; Malgorzata Sidorczuk-Lesthuruge; Holly Ashlene Rance; Kay Padget; Graham Hunter Jackson; Noritaka Adachi; Caroline A Austin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-21       Impact factor: 11.205

2.  Role for topoisomerase 1 in transcription-associated mutagenesis in yeast.

Authors:  Malcolm J Lippert; Nayun Kim; Jang-Eun Cho; Ryan P Larson; Nathan E Schoenly; Shannon H O'Shea; Sue Jinks-Robertson
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-21       Impact factor: 11.205

Review 3.  Topoisomerase-mediated chromosomal break repair: an emerging player in many games.

Authors:  Mohamed E Ashour; Reham Atteya; Sherif F El-Khamisy
Journal:  Nat Rev Cancer       Date:  2015-02-19       Impact factor: 60.716

4.  A phase I trial of talazoparib and irinotecan with and without temozolomide in children and young adults with recurrent or refractory solid malignancies.

Authors:  Sara M Federico; Alberto S Pappo; Natasha Sahr; April Sykes; Olivia Campagne; Clinton F Stewart; Michael R Clay; Armita Bahrami; Mary B McCarville; Sue C Kaste; Victor M Santana; Sara Helmig; Jessica Gartrell; Anang Shelat; Rachel C Brennan; Dana Hawkins; Kimberly Godwin; Michael W Bishop; Wayne L Furman; Elizabeth Stewart
Journal:  Eur J Cancer       Date:  2020-08-11       Impact factor: 9.162

5.  Pan-cancer analysis of whole genomes.

Authors: 
Journal:  Nature       Date:  2020-02-05       Impact factor: 49.962

6.  Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae.

Authors:  Diane T Takahashi; Guenaelle Burguiere-Slezak; Patricia Auffret Van der Kemp; Serge Boiteux
Journal:  Proc Natl Acad Sci U S A       Date:  2010-12-21       Impact factor: 11.205

7.  Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements.

Authors:  Michael C Haffner; Martin J Aryee; Antoun Toubaji; David M Esopi; Roula Albadine; Bora Gurel; William B Isaacs; G Steven Bova; Wennuan Liu; Jianfeng Xu; Alan K Meeker; George Netto; Angelo M De Marzo; William G Nelson; Srinivasan Yegnasubramanian
Journal:  Nat Genet       Date:  2010-07-04       Impact factor: 38.330

8.  Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors.

Authors:  Anish Thomas; Christophe E Redon; Linda Sciuto; Emerson Padiernos; Jiuping Ji; Min-Jung Lee; Akira Yuno; Sunmin Lee; Yiping Zhang; Lan Tran; William Yutzy; Arun Rajan; Udayan Guha; Haobin Chen; Raffit Hassan; Christine C Alewine; Eva Szabo; Susan E Bates; Robert J Kinders; Seth M Steinberg; James H Doroshow; Mirit I Aladjem; Jane B Trepel; Yves Pommier
Journal:  J Clin Oncol       Date:  2017-12-18       Impact factor: 50.717

Review 9.  Recent developments in topoisomerase-targeted cancer chemotherapy.

Authors:  KirkE Hevener; Tatsiana A Verstak; Katie E Lutat; Daniel L Riggsbee; Jeremiah W Mooney
Journal:  Acta Pharm Sin B       Date:  2018-07-25       Impact factor: 11.413

10.  The repertoire of mutational signatures in human cancer.

Authors:  Ludmil B Alexandrov; Jaegil Kim; Gad Getz; Steven G Rozen; Michael R Stratton; Nicholas J Haradhvala; Mi Ni Huang; Alvin Wei Tian Ng; Yang Wu; Arnoud Boot; Kyle R Covington; Dmitry A Gordenin; Erik N Bergstrom; S M Ashiqul Islam; Nuria Lopez-Bigas; Leszek J Klimczak; John R McPherson; Sandro Morganella; Radhakrishnan Sabarinathan; David A Wheeler; Ville Mustonen
Journal:  Nature       Date:  2020-02-05       Impact factor: 49.962
  10 in total

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