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Literature DB >> 3513938

Methotrexate resistance and gene amplification. Mechanisms and implications.

R T Schimke.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 1986 PMID： 3513938 DOI： 10.1002/1097-0142(19860515)57:10<1912::aid-cncr2820571004>3.0.co;2-o

Source DB: PubMed Journal: Cancer ISSN： 0008-543X Impact factor: 6.860

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18 in total

Review 1. Diagnosis and classification of the small round-cell tumors of childhood.

Authors: S L Cohn
Journal: Am J Pathol Date: 1999-07 Impact factor: 4.307

2. Gene amplification confers glyphosate resistance in Amaranthus palmeri.

Authors: Todd A Gaines; Wenli Zhang; Dafu Wang; Bekir Bukun; Stephen T Chisholm; Dale L Shaner; Scott J Nissen; William L Patzoldt; Patrick J Tranel; A Stanley Culpepper; Timothy L Grey; Theodore M Webster; William K Vencill; R Douglas Sammons; Jiming Jiang; Christopher Preston; Jan E Leach; Philip Westra
Journal: Proc Natl Acad Sci U S A Date: 2009-12-14 Impact factor: 11.205

3. Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression.

Authors: Matthew Spencer; Nathan Max; Joanna Ireland; Zhongcheng Zou; Ruipeng Wang; Peter Sun
Journal: Protein Expr Purif Date: 2017-08-24 Impact factor: 1.650

4. DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair.

Authors: J T Drummond; J Genschel; E Wolf; P Modrich
Journal: Proc Natl Acad Sci U S A Date: 1997-09-16 Impact factor: 11.205

5. In vivo and in vitro investigations on biological effects of aromatic bis-(2-chloroethyl)amino-bisphosphonic acids, new agents proposed for chemotherapy of bone tumors: cytostatic activity in rat osteosarcoma; toxicity and genotoxicity in liver and bone marrow; mutagenicity in S. typhimurium.

Authors: B L Pool; M Berger; J R Schlehofer; F Wingen
Journal: Invest New Drugs Date: 1988-06 Impact factor: 3.850

Methotrexate resistance and gene amplification. Mechanisms and implications.

Review 1. Diagnosis and classification of the small round-cell tumors of childhood.

2. Gene amplification confers glyphosate resistance in Amaranthus palmeri.

3. Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression.

4. DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair.

5. In vivo and in vitro investigations on biological effects of aromatic bis-(2-chloroethyl)amino-bisphosphonic acids, new agents proposed for chemotherapy of bone tumors: cytostatic activity in rat osteosarcoma; toxicity and genotoxicity in liver and bone marrow; mutagenicity in S. typhimurium.

6. A subset of herpes simplex virus replication genes induces DNA amplification within the host cell genome.

7. Analysis of gene amplification in human tumor cell lines.

8. Development of an improved mammalian overexpression method for human CD62L.

9. Mechanism-based model for tumor drug resistance.

10. Protection against zinc toxicity by metallothionein and zinc transporter 1.