Alfred B Engelberg1, Jerry Avorn1, Aaron S Kesselheim1. 1. From the Engelberg Foundation, Palm Beach, FL (A.B.E.); and the Program on Regulation, Therapeutics, and Law, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School - both in Boston (J.A., A.S.K.).