Literature DB >> 3513714

How to use a rotahaler.

S Pedersen.   

Abstract

The bronchodilator response after five different modes of salbutamol inhalation by rotahaler was assessed in 15 asthmatic children in a double blind cross over study. Inspiratory flow rates lower than 50 litres/minute were associated with a significant reduction in response compared with flow rates higher than 60 litres/minute, but tilting the head back during inhalation and holding the breath for 10 seconds had no significant effect on bronchodilation. Peak inspiratory flow rates measured in 150 normal children and 13 asthmatic children with acute wheeze showed that many young children and many children with severe bronchoconstriction were unable to generate a sufficiently high inspiratory flow rate to obtain maximum benefit from rotahaler treatment. Children using a rotahaler should be taught to inhale as quickly as possible and not with a quiet deep breath as recommended in the instruction leaflets.

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Year:  1986        PMID: 3513714      PMCID: PMC1777545          DOI: 10.1136/adc.61.1.11

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  4 in total

1.  Treatment of acute bronchoconstriction in children with use of a tube spacer aerosol and a dry powder inhaler.

Authors:  S Pedersen
Journal:  Allergy       Date:  1985-05       Impact factor: 13.146

2.  Pressurized aerosol inhaler technique: how important are inhalation from residual volume, inspiratory flow rate and the time interval between puffs?

Authors:  P Lawford; D McKenzie
Journal:  Br J Dis Chest       Date:  1983-07

3.  Pressurized bronchodilator aerosol technique: influence of breath-holding time and relationship of inhaler to the mouth.

Authors:  P Lawford
Journal:  Br J Dis Chest       Date:  1982-07

4.  Effect of lung function and mode of inhalation on penetration of aerosol into the human lung.

Authors:  D Pavia; M L Thomson; S W Clarke; H S Shannon
Journal:  Thorax       Date:  1977-04       Impact factor: 9.139

  4 in total
  12 in total

1.  Influence of inspiratory flow rate upon the effect of a Turbuhaler.

Authors:  S Pedersen; O R Hansen; G Fuglsang
Journal:  Arch Dis Child       Date:  1990-03       Impact factor: 3.791

2.  Particle size selection device for use with the Turbohaler.

Authors:  M L Everard; S G Devadason; P N Le Souef
Journal:  Thorax       Date:  1996-05       Impact factor: 9.139

3.  Inhalation treatment for asthma.

Authors:  J Reiser; J O Warner
Journal:  Arch Dis Child       Date:  1986-01       Impact factor: 3.791

Review 4.  The Impact of Inspiratory Flow Rate on Drug Delivery to the Lungs with Dry Powder Inhalers.

Authors:  Jeffry Weers; Andy Clark
Journal:  Pharm Res       Date:  2016-10-13       Impact factor: 4.200

5.  Need for a comparative performance standard for dry powder inhalers.

Authors:  R Richards; M Saunders
Journal:  Thorax       Date:  1993-11       Impact factor: 9.139

Review 6.  Antiasthma drug delivery. What is on the horizon?

Authors:  J C Virchow; C Kroegel; H Matthys
Journal:  Clin Pharmacokinet       Date:  1994-08       Impact factor: 6.447

7.  Pseudomonas aeruginosa antibodies in blood spots from patients with cystic fibrosis.

Authors:  V Thanasekaraan; M S Wiseman; R J Rayner; E J Hiller; D J Shale
Journal:  Arch Dis Child       Date:  1989-11       Impact factor: 3.791

8.  Controller Inhalers: Overview of Devices, Instructions for Use, Errors, and Interventions to Improve Technique.

Authors:  Patrick K Gleeson; Scott Feldman; Andrea J Apter
Journal:  J Allergy Clin Immunol Pract       Date:  2020-03-12

9.  Inhalation therapy in asthma.

Authors:  G Di Benedetto; S W Clarke
Journal:  J R Soc Med       Date:  1992-01       Impact factor: 18.000

10.  Effect of inhaler design variables on paediatric use of dry powder inhalers.

Authors:  Anne J Lexmond; Tonnis J Kruizinga; Paul Hagedoorn; Bart L Rottier; Henderik W Frijlink; Anne H de Boer
Journal:  PLoS One       Date:  2014-06-05       Impact factor: 3.240

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