Literature DB >> 35125731

Acute Promyelocytic Leukemia with t(2;3): An Unusual Additional Chromosomal Abnormality.

Smeeta Gajendra1, Anil Kumar Yadav2, Manorama Bhargava3.   

Abstract

Acute promyelocytic leukemia is a distinct subset of acute myeloid leukemia with characteristic clinical, morphological and genetic features. The gene product PML-RAR alpha resulting from reciprocal t(15;17) translocation, plays a pivotal role in the pathogenesis of acute promyelocytic leukemia and classified as favorable cytogenetic features. We are describing an unusual additional chromosomal abnormality t(2;3) in APL patient. © Indian Society of Hematology and Blood Transfusion 2021.

Entities:  

Keywords:  Acute promyelocytic leukemia; Additional chromosomal abnormality; Karyotype; t(2;3)

Year:  2021        PMID： 35125731      PMCID： PMC8804123          DOI： 10.1007/s12288-021-01468-z

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  2 in total

1.  Translocation t(2;3)(p15-23;q26-27) in myeloid malignancies: report of 21 new cases, clinical, cytogenetic and molecular genetic features.

Authors:  M Stevens-Kroef; B Poppe; S van Zelderen-Bhola; E van den Berg; M van der Blij-Philipsen; A Geurts van Kessel; R Slater; G Hamers; L Michaux; F Speleman; A Hagemeijer
Journal:  Leukemia       Date:  2004-06       Impact factor: 11.528

2.  A case of acute promyelocytic leukemia variant with derivative chromosome 3 der(3)t(3;8) associated with 8q partial gain.

Authors:  Filomena Nozza; Gabriella Vona; Stefania Trino; Fiorella D'Auria; Francesco La Rocca; Vitina Grieco; Luciana Possidente; Luciana De Luca; Pellegrino Musto
Journal:  Mol Cytogenet       Date:  2019-07-05       Impact factor: 2.009
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.