Literature DB >> 35123657

Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression.

David Leib1, Yong Hong Chen1, Alex Mas Monteys2, Beverly L Davidson3.   

Abstract

Entities:  

Keywords:  adeno-associated virus; astrocytes; conversion; gene therapy; neurodegeneration; neurons; transdifferentiation

Mesh：

Substances：

Year:  2022        PMID： 35123657      PMCID： PMC8899704          DOI： 10.1016/j.ymthe.2022.01.028

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  33 in total

1.  Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo.

Authors:  Yueguang Liu; Qinglong Miao; Jiacheng Yuan; Su'e Han; Panpan Zhang; Sanlan Li; Zhiping Rao; Wenlong Zhao; Qian Ye; Junlan Geng; Xiaohui Zhang; Leping Cheng
Journal:  J Neurosci       Date:  2015-06-24       Impact factor: 6.167

2.  Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair.

Authors:  Annalisa Buffo; Milan R Vosko; Dilek Ertürk; Gerhard F Hamann; Mathias Jucker; David Rowitch; Magdalena Götz
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-05       Impact factor: 11.205

3.  Directing astroglia from the cerebral cortex into subtype specific functional neurons.

Authors:  Christophe Heinrich; Robert Blum; Sergio Gascón; Giacomo Masserdotti; Pratibha Tripathi; Rodrigo Sánchez; Steffen Tiedt; Timm Schroeder; Magdalena Götz; Benedikt Berninger
Journal:  PLoS Biol       Date:  2010-05-18       Impact factor: 8.029

4.  Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia.

Authors:  Benedikt Berninger; Marcos R Costa; Ursula Koch; Timm Schroeder; Bernd Sutor; Benedikt Grothe; Magdalena Götz
Journal:  J Neurosci       Date:  2007-08-08       Impact factor: 6.167

5.  Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi.

Authors:  Jodi L McBride; Ryan L Boudreau; Scott Q Harper; Patrick D Staber; Alex Mas Monteys; Inâs Martins; Brian L Gilmore; Haim Burstein; Richard W Peluso; Barry Polisky; Barrie J Carter; Beverly L Davidson
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-08       Impact factor: 11.205

6.  Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease.

Authors:  Zheng Wu; Matthew Parry; Xiao-Yi Hou; Min-Hui Liu; Hui Wang; Rachel Cain; Zi-Fei Pei; Yu-Chen Chen; Zi-Yuan Guo; Sambangi Abhijeet; Gong Chen
Journal:  Nat Commun       Date:  2020-02-27       Impact factor: 14.919

7.  Reversing a model of Parkinson's disease with in situ converted nigral neurons.

Authors:  Hao Qian; Xinjiang Kang; Jing Hu; Dongyang Zhang; Zhengyu Liang; Fan Meng; Xuan Zhang; Yuanchao Xue; Roy Maimon; Steven F Dowdy; Neal K Devaraj; Zhuan Zhou; William C Mobley; Don W Cleveland; Xiang-Dong Fu
Journal:  Nature       Date:  2020-06-24       Impact factor: 49.962

8.  Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex.

Authors:  Zongqin Xiang; Liang Xu; Minhui Liu; Qingsong Wang; Wen Li; Wenliang Lei; Gong Chen
Journal:  Neural Regen Res       Date:  2021-04       Impact factor: 5.135

9.  Glial cells generate neurons: the role of the transcription factor Pax6.

Authors:  Nico Heins; Paolo Malatesta; Francesco Cecconi; Masato Nakafuku; Kerry Lee Tucker; Michael A Hack; Prisca Chapouton; Yves-Alain Barde; Magdalena Götz
Journal:  Nat Neurosci       Date:  2002-04       Impact factor: 24.884

10.  Environmental impact on direct neuronal reprogramming in vivo in the adult brain.

Authors:  Andrew Grande; Kyoko Sumiyoshi; Alejandro López-Juárez; Jennifer Howard; Bhuvaneswari Sakthivel; Bruce Aronow; Kenneth Campbell; Masato Nakafuku
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919
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  4 in total

Review 1.  In vivo glia-to-neuron conversion: pitfalls and solutions.

Authors:  Lei-Lei Wang; Chun-Li Zhang
Journal:  Dev Neurobiol       Date:  2022-05-23       Impact factor: 3.102

2.  Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson's disease.

Authors:  Weizhao Chen; Qiongping Zheng; Qiaoying Huang; Shanshan Ma; Mingtao Li
Journal:  Elife       Date:  2022-05-10       Impact factor: 8.713

3.  Ascl1 phospho-site mutations enhance neuronal conversion of adult cortical astrocytes in vivo.

Authors:  Hussein Ghazale; EunJee Park; Lakshmy Vasan; James Mester; Fermisk Saleh; Andrea Trevisiol; Dawn Zinyk; Vorapin Chinchalongporn; Mingzhe Liu; Taylor Fleming; Oleksandr Prokopchuk; Natalia Klenin; Deborah Kurrasch; Maryam Faiz; Bojana Stefanovic; JoAnne McLaurin; Carol Schuurmans
Journal:  Front Neurosci       Date:  2022-08-18       Impact factor: 5.152

4.  Transcriptomic analyses of NeuroD1-mediated astrocyte-to-neuron conversion.

Authors:  Ning-Xin Ma; Brendan Puls; Gong Chen
Journal:  Dev Neurobiol       Date:  2022-05-23       Impact factor: 3.102
  4 in total

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