Anne J Huiberts1, Yolande M Vermeeren1,2, Thomas van Bemmel1,2, Renske G Wieberdink1,3, Cornelia H M van Jaarsveld4, Tizza P Zomer5. 1. Lyme Center Apeldoorn, Gelre Hospital, P.O. Box 9014, 7300 DS, Apeldoorn, The Netherlands. 2. Department of Internal Medicine, Gelre Hospital, Apeldoorn, The Netherlands. 3. Department of Neurology, Gelre Hospital, Apeldoorn, The Netherlands. 4. Department of Primary and Community Care, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands. 5. Lyme Center Apeldoorn, Gelre Hospital, P.O. Box 9014, 7300 DS, Apeldoorn, The Netherlands. t.zomer@gelre.nl.
Abstract
INTRODUCTION: Little is known on coping strategies in patients with chronic symptoms suspected of Lyme borreliosis (LB). Different coping strategies might influence quality of life (QoL). We assessed coping strategies and QoL in patients with chronic symptoms suspected of LB. METHODS: Adult patients referred to the Lyme Center Apeldoorn were included (November 2019-April 2021). Participants completed the RAND-36 to assess QoL and the Utrecht Coping List to assess coping strategies. Patient data were extracted from medical records. Patients were categorized based on clinical LB and serology. Linear regression analyses were conducted to examine an association between coping strategies and QoL subscales. RESULTS: Included were 201 patients. Patients suspected of LB had a different coping profile and lower QoL compared to the reference population. Patients with negative serology and no clinical LB scored lowest on all QoL subscales. In multivariate analyses, correcting for age, gender, comorbidity, and patient category, a negative association was found between passive coping and the QoL subscales physical functioning (β(SE) = - 1.1(0.5)), social functioning (β(SE) = - 3.3(0.5)), role limitations (emotional) (β(SE) = - 5.5(0.8)), mental health (β(SE) = - 3.7(0.3)), vitality (β(SE) = - 2.3(0.3)), pain (β(SE) = - 2.3(0.5)), and general health (β(SE) = - 2.7(0.3)). A negative association was also found between palliative coping and the QoL subscale role limitations (physical) (β(SE) = - 1.8(0.6)) and between expressing emotions and mental health (β(SE) = - 1.3(0.6)). A positive association was found between active coping and the QoL subscales mental health (β(SE) = 1.0(0.3)) and role limitations (emotional) (β(SE) = 1.9(0.8)). CONCLUSION: In patients suspected of LB, dysfunctional coping strategies were associated with worse quality of life. There is a need for interventions that can guide patients with chronic symptoms suspected of LB towards more active coping and increase QoL.
INTRODUCTION: Little is known on coping strategies in patients with chronic symptoms suspected of Lyme borreliosis (LB). Different coping strategies might influence quality of life (QoL). We assessed coping strategies and QoL in patients with chronic symptoms suspected of LB. METHODS: Adult patients referred to the Lyme Center Apeldoorn were included (November 2019-April 2021). Participants completed the RAND-36 to assess QoL and the Utrecht Coping List to assess coping strategies. Patient data were extracted from medical records. Patients were categorized based on clinical LB and serology. Linear regression analyses were conducted to examine an association between coping strategies and QoL subscales. RESULTS: Included were 201 patients. Patients suspected of LB had a different coping profile and lower QoL compared to the reference population. Patients with negative serology and no clinical LB scored lowest on all QoL subscales. In multivariate analyses, correcting for age, gender, comorbidity, and patient category, a negative association was found between passive coping and the QoL subscales physical functioning (β(SE) = - 1.1(0.5)), social functioning (β(SE) = - 3.3(0.5)), role limitations (emotional) (β(SE) = - 5.5(0.8)), mental health (β(SE) = - 3.7(0.3)), vitality (β(SE) = - 2.3(0.3)), pain (β(SE) = - 2.3(0.5)), and general health (β(SE) = - 2.7(0.3)). A negative association was also found between palliative coping and the QoL subscale role limitations (physical) (β(SE) = - 1.8(0.6)) and between expressing emotions and mental health (β(SE) = - 1.3(0.6)). A positive association was found between active coping and the QoL subscales mental health (β(SE) = 1.0(0.3)) and role limitations (emotional) (β(SE) = 1.9(0.8)). CONCLUSION: In patients suspected of LB, dysfunctional coping strategies were associated with worse quality of life. There is a need for interventions that can guide patients with chronic symptoms suspected of LB towards more active coping and increase QoL.
Authors: Anneleen Berende; Hadewych J M ter Hofstede; Fidel J Vos; Henriët van Middendorp; Michiel L Vogelaar; Mirjam Tromp; Frank H van den Hoogen; A Rogier T Donders; Andrea W M Evers; Bart Jan Kullberg Journal: N Engl J Med Date: 2016-03-31 Impact factor: 91.245
Authors: Hedwig D Vrijmoeth; Jeanine Ursinus; Margriet G Harms; Tizza P Zomer; Stefanie A Gauw; Anna D Tulen; Kristin Kremer; Hein Sprong; Hans Knoop; Yolande M Vermeeren; Barend van Kooten; Leo A B Joosten; Bart-Jan Kullberg; Joppe W R Hovius; Cees C van den Wijngaard Journal: BMC Infect Dis Date: 2019-04-15 Impact factor: 3.090
Authors: Jeanine Ursinus; Hedwig D Vrijmoeth; Margriet G Harms; Anna D Tulen; Hans Knoop; Stefanie A Gauw; Tizza P Zomer; Albert Wong; Ingrid H M Friesema; Yolande M Vermeeren; Leo A B Joosten; Joppe W Hovius; Bart Jan Kullberg; Cees C van den Wijngaard Journal: Lancet Reg Health Eur Date: 2021-05-27
Authors: Agnetha Hofhuis; Sita Bennema; Margriet Harms; Arnold J H van Vliet; Willem Takken; Cees C van den Wijngaard; Wilfrid van Pelt Journal: BMC Public Health Date: 2016-05-23 Impact factor: 3.295