Literature DB >> 3511906

Muscle proteins related to microtubule associated protein-2 are substrates for an insulin-stimulatable kinase.

T W Sturgill, L B Ray.   

Abstract

High molecular weight muscle protein(s), present as a "doublet" (approximately 320 and approximately 290 kDa apparent molecular weight) in partially purified preparations of inhibitor-2 from rabbit skeletal muscle, and homogeneous bovine brain microtubule associated protein-2 are both in vitro substrates for a soluble insulin-stimulatable serine/threonine kinase in 3T3-L1 adipocytes. The high molecular weight muscle substrate "doublet" was specifically immunoprecipitated by affinity-purified anti-microtubule associated protein-2 antibody.

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Year:  1986        PMID: 3511906     DOI: 10.1016/s0006-291x(86)80457-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  20 in total

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