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Literature DB >> 3511863

Growth of human B cell colonies from peripheral blood of patients with systemic lupus erythematosus.

A C Fay, S Price, A Trudgett, J D McCrea, M Haire, M W Boyd, T A McNeill.

Abstract

Human B cell colonies were grown from peripheral blood of 12 patients with systemic lupus erythematosus (SLE) and from 12 healthy control subjects. The SLE group showed a large increase (p less than 0.001) in the number of colony forming cells (CFC) present in peripheral blood as compared with controls. The CFC were of the pre-B cell type. There was also a loss of OKT8+ cell inhibition of B cell colony growth in the SLE group compared with control subjects.

Entities: Disease Species

Mesh：

Year: 1986 PMID： 3511863 PMCID： PMC1001827 DOI： 10.1136/ard.45.2.95

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

20 in total

1. Biochemical and physiochemical characteristics of a pre-B cell stimulating factor produced by the plasmacytoma cell line LICR LON HMY2.

Authors: A Trudgett; A C Fay; J M Thompson; T A McNeill
Journal: Clin Exp Immunol Date: 1985-03 Impact factor: 4.330

2. Comparison in T- and B-cell markers in patients with Sjögren's syndrome and systemic lupus erythematosus.

Authors: C Morimoto; E L Reinherz; L M Nadler; J A Distaso; A D Steinberg; S F Schlossman
Journal: Clin Immunol Immunopathol Date: 1982-02

Review 3. Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system.

Authors: T A Waldmann; S Broder
Journal: Adv Immunol Date: 1982 Impact factor: 3.543

4. In vitro immune response of human peripheral lymphocytes. VI. Distribution and characterization of precursors for PHA- and protein A-induced colony-forming B cells.

Authors: T Kuritani; T Kishimoto; A Muraguchi; Y Yamamura
Journal: J Immunol Date: 1980-12 Impact factor: 5.422

Growth of human B cell colonies from peripheral blood of patients with systemic lupus erythematosus.

1. Biochemical and physiochemical characteristics of a pre-B cell stimulating factor produced by the plasmacytoma cell line LICR LON HMY2.

2. Comparison in T- and B-cell markers in patients with Sjögren's syndrome and systemic lupus erythematosus.

Review 3. Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system.

4. In vitro immune response of human peripheral lymphocytes. VI. Distribution and characterization of precursors for PHA- and protein A-induced colony-forming B cells.

5. Characteristics and differential T-cell dependency of human B-cell colony precursors.

6. In vivo cyclic change in B-lymphocyte susceptibility to T-cell control.

7. Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus.

8. Spontaneous and pokeweed mitogen-induced plaque-forming cells in systemic lupus erythematosus.

9. Circulating and pokeweed mitogen-induced immunoglobulin-secreting cells in systemic lupus erythematosus.

10. Human B lymphocyte subsets. I. IgG-bearing B cell response to pokeweed mitogen.

1. Spontaneous production of B cell growth factors by SLE lymphocytes.