| Literature DB >> 3511719 |
S M Hsu, Y S Ho, P J Li, J Monheit, H J Ree, K Sheibani, C D Winberg.
Abstract
Anti-Leu M1 generally does not stain the lymphocytic and histiocytic (L&H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin's disease. However, the authors found that after neuraminidase treatment for removal of sialic acid, the L&H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L&H cells differ from the Reed-Sternberg cells in other types of Hodgkin's disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.Entities:
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Year: 1986 PMID: 3511719 PMCID: PMC1888104
Source DB: PubMed Journal: Am J Pathol ISSN: 0002-9440 Impact factor: 4.307