| Literature DB >> 35113777 |
Ibrahim Mohammed1, Areej Nauman1, Pradipta Paul1, Sanjith Ganesan1, Kuan-Han Chen1, Syed Muhammad Saad Jalil1, Shahd H Jaouni1, Hussam Kawas1, Wafa A Khan1, Ahamed Lazim Vattoth1, Yasmeen Alavi Al-Hashimi1, Ahmed Fares1, Rached Zeghlache1, Dalia Zakaria1.
Abstract
With the relatively rapid development of the COVID-19 pandemic, vaccine development has become crucial for limiting disease transmission. The accelerated growth in the approved COVID-19 vaccines has sparked concerns about their efficacies which have been assessed by many studies. This systematic review compares the efficacy and effectiveness of seven COVID-19 vaccines. A comprehensive systematic literature search was performed using several databases to identify studies reporting the effectiveness or the efficacy of the vaccines. Only 42 studies met our inclusion criteria, which revealed that the COVID-19 vaccines have successfully reduced the rates of infections, severity, hospitalization, and mortality among the different populations. The full-dose regimen of the Pfizer/BioNTech vaccine is the most effective against infections with the B.1.1.7 and B.1.351 variants. Despite of the high effectiveness of some of the COVID-19 vaccines, more efforts are required to test their effectiveness against the other newly emerging variants.Entities:
Keywords: COVID-19; effectiveness; efficacy; vaccine
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Year: 2022 PMID： 35113777 PMCID： PMC8862168 DOI： 10.1080/21645515.2022.2027160
Source DB: PubMed Journal: Hum Vaccin Immunother ISSN： 2164-5515 Impact factor: 3.452