Literature DB >> 35111318

Acupuncture (superficial dry-needling) as a treatment for chronic postherpetic neuralgia - a randomized clinical trial.

Martin Sollie1,2,3, Robert Pind4, Christoffer Bing Madsen1,2, Jens Ahm Sørensen1,2,3.   

Abstract

BACKGROUND: Postherpetic neuralgia is a painful condition where finding sufficient treatment poses a great challenge. Acupuncture is often used as an alternative treatment for these pains, yet no randomized trials, using a sham-placebo have been performed to confirm its effect. Our objective was to investigate the efficacy of acupuncture compared to sham-acupuncture when treating chronic postherpetic dermal pain.
METHODS: We performed a sham-controlled double-blinded randomized clinical trial (RCT) with two arms. The intervention group received superficial dry-needling, and the control group received sham acupuncture using blunted needles. Twenty-six patients received two treatments. They filled out questionnaires at baseline and 1 month after treatment: (1) average and maximum pain (Numeric Rating Scale), (2) neuropathic pain (Neuropathic Pain Scale Inventory) and (3) Quality of Life (QoL) (Short-form 36).
RESULTS: Thirteen patients were allocated to the intervention group and 15 to the control group. We did not detect any significant changes in levels of pain and neuropathic pain. One QoL parameter, regarding emotional problems, reached a level of statistical significance. The sham-blinding was successful. This is the first RCT on the effect of acupuncture (superficial dry-needling) on postherpetic neuralgia (PHN), using a sham procedure as control. We observed no significant changes or tendencies in the measured levels of pain. One QoL parameter had significant improvement in the intervention group compared to the control group.
CONCLUSION: In conclusion, acupuncture was not superior to treatment with sham acupuncture. Though individual patients may experience some pain relief from acupuncture, our results do not support the routine use of this type of acupuncture to treat PHN. © The British Pain Society 2021.

Entities:  

Keywords:  Acupuncture; PHN; postherpetic neuralgia; superficial dry-needling

Year:  2021        PMID: 35111318      PMCID: PMC8801694          DOI: 10.1177/20494637211023075

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


  42 in total

Review 1.  Treatment of postherpetic neuralgia: a review of therapeutic options.

Authors:  Charles E Argoff; Nathaniel Katz; Miroslav Backonja
Journal:  J Pain Symptom Manage       Date:  2004-10       Impact factor: 3.612

2.  [Systematic assessment of acupuncture for treatment of herpes zoster in domestic clinical studies].

Authors:  Xian-min Yu; Guo-miao Zhu; Yue-lai Chen; Min Fang; You-nan Chen
Journal:  Zhongguo Zhen Jiu       Date:  2007-07

3.  Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model.

Authors:  Jun Mo Kang; Hi Joon Park; Yeong Gon Choi; Il Hwan Choe; Jae Hyun Park; Yong Sik Kim; Sabina Lim
Journal:  Brain Res       Date:  2006-12-14       Impact factor: 3.252

4.  Tests of data quality, scaling assumptions, and reliability of the Danish SF-36.

Authors:  J B Bjorner; M T Damsgaard; T Watt; M Groenvold
Journal:  J Clin Epidemiol       Date:  1998-11       Impact factor: 6.437

5.  Proliferation of non-neuronal cells in spinal cords of irradiated, immature rats following transection of the sciatic nerve.

Authors:  S A Gilmore
Journal:  Anat Rec       Date:  1975-04

6.  Is acupuncture effective for the treatment of chronic pain? A systematic review.

Authors:  Jeanette Ezzo; Brian Berman; Victoria A Hadhazy; Alejandro R Jadad; Lixing Lao; Betsy B Singh
Journal:  Pain       Date:  2000-06       Impact factor: 6.961

7.  The impact of herpes zoster and post-herpetic neuralgia on quality-of-life.

Authors:  Robert W Johnson; Didier Bouhassira; George Kassianos; Alain Leplège; Kenneth E Schmader; Thomas Weinke
Journal:  BMC Med       Date:  2010-06-21       Impact factor: 8.775

Review 8.  Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology.

Authors:  Theresa Mallick-Searle; Brett Snodgrass; Jeannine M Brant
Journal:  J Multidiscip Healthc       Date:  2016-09-21

Review 9.  Peripheral receptors and neuromediators involved in the antihyperalgesic effects of acupuncture: a state-of-the-art review.

Authors:  Maísa Maria Spagnol Trento; Ari Ojeda Ocampo Moré; Elisa Cristiana Winkelmann Duarte; Daniel Fernandes Martins
Journal:  Pflugers Arch       Date:  2021-01-20       Impact factor: 3.657

10.  Molecular mechanisms underlying the effects of acupuncture on neuropathic pain.

Authors:  Ziyong Ju; Huashun Cui; Xiaohui Guo; Huayuan Yang; Jinsen He; Ke Wang
Journal:  Neural Regen Res       Date:  2013-09-05       Impact factor: 5.135

View more
  1 in total

Review 1.  Potential mechanisms of acupuncture for neuropathic pain based on somatosensory system.

Authors:  Xin Ma; Wen Chen; Na-Na Yang; Lu Wang; Xiao-Wan Hao; Chun-Xia Tan; Hong-Ping Li; Cun-Zhi Liu
Journal:  Front Neurosci       Date:  2022-09-20       Impact factor: 5.152

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.