Literature DB >> 35110909

Complications and Outcomes of Diaphragm Surgeries in Epithelial Ovarian Malignancies.

Amrita Datta1, Ajit Sebastian1, Rachel George Chandy1, Vinotha Thomas1, Dhanya Susan Thomas1, Reka Karuppusami2, Anitha Thomas1, Abraham Peedicayil1.   

Abstract

To achieve optimal debulking, cytoreductive surgery often involves diaphragm stripping. We describe our complications and survival outcomes after diaphragm surgery in epithelial ovarian cancer. A retrospective analysis on patients with advanced stage epithelial ovarian cancer between January 2012 and September 2019. The details of the diaphragmatic resections and stripping and their complications were looked into. During the study period, 616 patients with epithelial ovarian cancers were operated of which, 81 (13.2%) had diaphragm surgery. The majority underwent diaphragm stripping (60%) while 33% had resection and 7% cases had diaphragmatic nodule excision. Optimal debulking was achieved in 89% of cases. The complexity of surgery was intermediate in 64% of patients and complex in 33% as per Aletti's scoring. Mean operating time was 300 min (SD113). Moderate to severe pleural effusion was seen in 26 (32. %) patients necessitating pleural tapping in 16% and single lumen pleurex catheter insertion in 11%. Median recurrence-free and overall survival were 22 (95% CI 16.9-27) and 32 months (95% CI 25.5-38) respectively. Diaphragm stripping and resection is an important step in achieving optimal debulking of advanced and recurrent ovarian cancer. Diaphragmatic disease clearance is a necessary skill to be acquired by the gynaecologic oncology surgeons. Choosing the patients correctly and anticipation of complications can reduce morbidity and mortality. © Indian Association of Surgical Oncology 2021.

Entities:  

Keywords:  Diaphragmatic resection; Diaphragmatic stripping; Optimal cytoreduction; Ovarian cancer

Year:  2021        PMID: 35110909      PMCID: PMC8764007          DOI: 10.1007/s13193-021-01438-x

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  33 in total

1.  Diaphragmatic surgery during primary cytoreduction for advanced ovarian cancer: peritoneal stripping versus diaphragmatic resection.

Authors:  Ignacio Zapardiel; Michele Peiretti; Vanna Zanagnolo; Roberto Biffi; Luca Bocciolone; Fabio Landoni; Giovanni Aletti; Nicoletta Colombo; Angelo Maggioni
Journal:  Int J Gynecol Cancer       Date:  2011-12       Impact factor: 3.437

2.  The role of diaphragmatic surgery during interval debulking after neoadjuvant chemotherapy: an analysis of 74 patients with advanced epithelial ovarian cancer.

Authors:  Dimitris Tsolakidis; Frederic Amant; Toon Van Gorp; Karin Leunen; Patrick Neven; Ignace Vergote
Journal:  Int J Gynecol Cancer       Date:  2010-05       Impact factor: 3.437

3.  Surgical treatment of diaphragm disease correlates with improved survival in optimally debulked advanced stage ovarian cancer.

Authors:  Giovanni D Aletti; Sean C Dowdy; Karl C Podratz; William A Cliby
Journal:  Gynecol Oncol       Date:  2005-09-22       Impact factor: 5.482

4.  What is the optimal goal of primary cytoreductive surgery for bulky stage IIIC epithelial ovarian carcinoma (EOC)?

Authors:  D S Chi; E L Eisenhauer; J Lang; J Huh; L Haddad; N R Abu-Rustum; Y Sonoda; D A Levine; M Hensley; R R Barakat
Journal:  Gynecol Oncol       Date:  2006-05-22       Impact factor: 5.482

5.  Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis.

Authors:  Robert E Bristow; Rafael S Tomacruz; Deborah K Armstrong; Edward L Trimble; F J Montz
Journal:  J Clin Oncol       Date:  2002-03-01       Impact factor: 44.544

Review 6.  Epithelial ovarian carcinoma: principles of primary surgery.

Authors:  W J Hoskins
Journal:  Gynecol Oncol       Date:  1994-12       Impact factor: 5.482

7.  Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.

Authors:  Freddie Bray; Jacques Ferlay; Isabelle Soerjomataram; Rebecca L Siegel; Lindsey A Torre; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2018-09-12       Impact factor: 508.702

8.  Diaphragmatic peritonectomy versus full thickness diaphragmatic resection and pleurectomy during cytoreduction in patients with ovarian cancer.

Authors:  P N J Pathiraja; R Garruto-Campanile; R Tozzi
Journal:  Int J Surg Oncol       Date:  2013-12-18

9.  Diaphragmatic Surgery and Related Complications In Primary Cytoreduction for Advanced Ovarian, Tubal, and Peritoneal Carcinoma.

Authors:  Shuang Ye; Tiancong He; Shanhui Liang; Xiaojun Chen; Xiaohua Wu; Huijuan Yang; Libing Xiang
Journal:  BMC Cancer       Date:  2017-05-05       Impact factor: 4.430

10.  Tozzi classification of diaphragmatic surgery in patients with stage IIIC-IV ovarian cancer based on surgical findings and complexity.

Authors:  Roberto Tozzi; Federico Ferrari; Joost Nieuwstad; Riccardo Garruto Campanile; Hooman Soleymani Majd
Journal:  J Gynecol Oncol       Date:  2019-09-02       Impact factor: 4.401

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