Literature DB >> 35110234

Surgical Treatment in Small-Cell Lung Cancer: Single-Center Experience and Survival.

Ahmet Ulusan1, İbrahim Emre Tunca1, Maruf Şanlı1, Ahmet Feridun Işık1.   

Abstract

OBJECTIVE: To evaluate the clinical outcomes of patients with different stages of small-cell lung cancer (SCLC) who underwent surgical treatment.
MATERIAL AND METHODS: This retrospective study consisted of 13 patients with SCLC at a tertiary care health center. This study was conducted between 2011 and 2018 at Gaziantep University Faculty of Medicine, Thoracic Surgery Department. Patient follow-up data were collected from medical files. Patients were analyzed according to age, sex, site of resection, clinical stage, pathological stage, recurrence, operation type, chemotherapy, radiotherapy.
RESULTS: The study group consisted of 3 females and 10 males (n = 13). The mean age of the patients was 65 ± 9.3 (52-85) years. The most common location of the primary tumor was the right upper lobe (6 patients, 46.2%). The mean tumor size was 4.36 ± 2.38 cm (1-8.5). In our study, 3 patients had already metastases (2 brain and 1 had metastases in more than 2 anatomic sites). Patients with solitary metastases, who underwent lung resection and metastasis excision had similar survival according to patients without metastases.
CONCLUSION: Our results show that surgical treatment in SCLC could be contributed to the survival of patients. Therefore, patients must be given a chance for surgery, especially considering that the advances in diagnostic and surgical capabilities have increased the likelihood of early diagnosis and effective surgery.

Entities:  

Year:  2021        PMID: 35110234      PMCID: PMC8975300          DOI: 10.5152/TurkThoracJ.2021.19140

Source DB:  PubMed          Journal:  Turk Thorac J        ISSN: 2148-7197


  23 in total

1.  Role of surgical resection for patients with limited disease-small cell lung cancer.

Authors:  Tomoyoshi Takenaka; Mitsuhiro Takenoyama; Eiko Inamasu; Tsukihisa Yoshida; Gouji Toyokawa; Kaname Nosaki; Fumihiko Hirai; Masafumi Yamaguchi; Mototsugu Shimokawa; Takashi Seto; Yukito Ichinose
Journal:  Lung Cancer       Date:  2015-01-23       Impact factor: 5.705

2.  Influence of surgical resection before and after chemotherapy on survival in small cell lung cancer.

Authors:  N Hara; M Ohta; Y Ichinose; A Motohiro; T Kuda; H Asoh; M Kawasaki
Journal:  J Surg Oncol       Date:  1991-05       Impact factor: 3.454

3.  Effect of initial resection of small-cell carcinoma of the lung: a review of Southwest Oncology Group Study 7628.

Authors:  G G Friess; J D McCracken; M L Troxell; R Pazdur; C A Coltman; H J Eyre
Journal:  J Clin Oncol       Date:  1985-07       Impact factor: 44.544

4.  Bolstering the case for lobectomy in stages I, II, and IIIA small-cell lung cancer using the National Cancer Data Base.

Authors:  Susan E Combs; Jacquelyn G Hancock; Daniel J Boffa; Roy H Decker; Frank C Detterbeck; Anthony W Kim
Journal:  J Thorac Oncol       Date:  2015-02       Impact factor: 15.609

5.  Long-Term Outcomes and Patterns of Failure After Surgical Resection of Small-Cell Lung Cancer.

Authors:  Bradley J Stish; Christopher L Hallemeier; Kenneth R Olivier; William S Harmsen; Mark S Allen; Yolanda I Garces
Journal:  Clin Lung Cancer       Date:  2015-02-21       Impact factor: 4.785

6.  Surgical resection of limited disease small cell lung cancer in the new era of platinum chemotherapy: Its time has come.

Authors:  Malcolm V Brock; Craig M Hooker; James E Syphard; William Westra; Li Xu; Anthony J Alberg; David Mason; Stephen B Baylin; James G Herman; Rex C Yung; Julie Brahmer; Charles M Rudin; David S Ettinger; Stephen C Yang
Journal:  J Thorac Cardiovasc Surg       Date:  2005-01       Impact factor: 5.209

7.  Long-term survival after surgical resection of liver metastasis from lung cancer.

Authors:  Akira Nagashima; Yuji Abe; Sosuke Yamada; Makoto Nakagawa; Takashi Yoshimatsu
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2004-06

Review 8.  Lung cancer surgery: an up to date.

Authors:  Nikolaos Baltayiannis; Michail Chandrinos; Dimitrios Anagnostopoulos; Paul Zarogoulidis; Kosmas Tsakiridis; Andreas Mpakas; Nikolaos Machairiotis; Nikolaos Katsikogiannis; Ioanna Kougioumtzi; Nikolaos Courcoutsakis; Konstantinos Zarogoulidis
Journal:  J Thorac Dis       Date:  2013-09       Impact factor: 2.895

9.  Adjuvant chemotherapy following surgical resection for small-cell carcinoma of the lung.

Authors:  F A Shepherd; W K Evans; R Feld; V Young; G A Patterson; R Ginsberg; E Johansen
Journal:  J Clin Oncol       Date:  1988-05       Impact factor: 44.544

10.  Surveillance epidemiology and end results evaluation of the role of surgery for stage I small cell lung cancer.

Authors:  James B Yu; Roy H Decker; Frank C Detterbeck; Lynn D Wilson
Journal:  J Thorac Oncol       Date:  2010-02       Impact factor: 15.609

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