Literature DB >> 35107032

The therapeutic potential of exosomes derived from different cell sources in liver diseases.

Yun Pan1, Wei-Feng Tan2, Mu-Qing Yang3, Ji-Yu Li3, David A Geller4.   

Abstract

Exosomes are small nanovesicles with a size of approximately 40-120 nm that are secreted from cells. They are involved in the regulation of cell homeostasis and mediate intercellular communication. In addition, they carry proteins, nucleic acids, and lipids that regulate the biological activity of receptor cells. Recent studies have shown that exosomes perform important functions in liver diseases. This review will focus on liver diseases (drug-induced liver injury, hepatic ischemia-reperfusion injury, liver fibrosis, acute liver failure, and hepatocellular carcinoma) and summarize the therapeutic potential of exosomes from different cell sources in liver disease.

Entities:  

Keywords:  exosomes; liver disease; role; therapeutic potential

Mesh：

Year:  2022        PMID： 35107032      PMCID： PMC8917924          DOI： 10.1152/ajpgi.00054.2021

Source DB:  PubMed          Journal:  Am J Physiol Gastrointest Liver Physiol        ISSN： 0193-1857            Impact factor:   4.052


  125 in total

1.  Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelines.

Authors:  Harshad Devarbhavi; Guruprasad Aithal; Sombat Treeprasertsuk; Hajime Takikawa; Yimin Mao; Saggere M Shasthry; Saeed Hamid; Soek Siam Tan; Cyriac Abby Philips; Jacob George; Wasim Jafri; Shiv K Sarin
Journal:  Hepatol Int       Date:  2021-02-27       Impact factor: 6.047

2.  Janus Gold Nanoplatform for Synergetic Chemoradiotherapy and Computed Tomography Imaging of Hepatocellular Carcinoma.

Authors:  Zheng Wang; Dan Shao; Zhimin Chang; Mengmeng Lu; Yingshuai Wang; Juan Yue; Dian Yang; Mingqiang Li; Qiaobing Xu; Wen-Fei Dong
Journal:  ACS Nano       Date:  2017-11-17       Impact factor: 15.881

3.  Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis.

Authors:  Tingfen Li; Yongmin Yan; Bingying Wang; Hui Qian; Xu Zhang; Li Shen; Mei Wang; Ying Zhou; Wei Zhu; Wei Li; Wenrong Xu
Journal:  Stem Cells Dev       Date:  2012-11-07       Impact factor: 3.272

4.  Histological outcome during long-term lamivudine therapy.

Authors:  Jules L Dienstag; Robert D Goldin; E Jenny Heathcote; H W L Hann; Mary Woessner; Sally L Stephenson; Stephen Gardner; D Fraser Gray; Eugene R Schiff
Journal:  Gastroenterology       Date:  2003-01       Impact factor: 22.682

5.  Acute liver failure: Summary of a workshop.

Authors:  William M Lee; Robert H Squires; Scott L Nyberg; Edward Doo; Jay H Hoofnagle
Journal:  Hepatology       Date:  2008-04       Impact factor: 17.425

6.  DNA Vectors Generating Engineered Exosomes Potential CTL Vaccine Candidates Against AIDS, Hepatitis B, and Tumors.

Authors:  Flavia Ferrantelli; Francesco Manfredi; Chiara Chiozzini; Simona Anticoli; Eleonora Olivetta; Claudia Arenaccio; Maurizio Federico
Journal:  Mol Biotechnol       Date:  2018-11       Impact factor: 2.695

7.  Towards elimination of hepatitis B and C in European Union and European Economic Area countries: monitoring the World Health Organization's global health sector strategy core indicators and scaling up key interventions.

Authors:  Erika F Duffell; Dagmar Hedrich; Otilia Mardh; Antons Mozalevskis
Journal:  Euro Surveill       Date:  2017-03-02

8.  Potentiating the efficacy of molecular targeted therapy for hepatocellular carcinoma by inhibiting the insulin-like growth factor pathway.

Authors:  Da-Liang Ou; Bin-Shyun Lee; Ya-Chi Chang; Liang-In Lin; Jun-Yang Liou; Chiun Hsu; Ann-Lii Cheng
Journal:  PLoS One       Date:  2013-06-20       Impact factor: 3.240

Review 9.  Ethical and Safety Issues of Stem Cell-Based Therapy.

Authors:  Vladislav Volarevic; Bojana Simovic Markovic; Marina Gazdic; Ana Volarevic; Nemanja Jovicic; Nebojsa Arsenijevic; Lyle Armstrong; Valentin Djonov; Majlinda Lako; Miodrag Stojkovic
Journal:  Int J Med Sci       Date:  2018-01-01       Impact factor: 3.738

10.  Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice.

Authors:  Young-Eun Cho; Wonhyo Seo; Do-Kyun Kim; Pyong-Gon Moon; Sang-Hyun Kim; Byung-Heon Lee; Byoung-Joon Song; Moon-Chang Baek
Journal:  Sci Rep       Date:  2018-10-30       Impact factor: 4.379
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  2 in total

Review 1.  Liver Regeneration by Hematopoietic Stem Cells: Have We Reached the End of the Road?

Authors:  Elena Konstantina Siapati; Maria G Roubelakis; George Vassilopoulos
Journal:  Cells       Date:  2022-07-27       Impact factor: 7.666

Review 2.  Insights into Exosome in the Intervertebral Disc: Emerging Role for Disc Homeostasis and Normal Function.

Authors:  Xin Zhao; Benchi Xu; Wei Duan; Le Chang; Rui Tan; Zhen Sun; Zhengxu Ye
Journal:  Int J Med Sci       Date:  2022-09-25       Impact factor: 3.642
  2 in total

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