Literature DB >> 35103122

Neurofibromatosis Type Two: A Case With Both Intracranial and Spinal Lesions.

Sandipta Banerjee1, Ajay Agarwal2.   

Abstract

We discuss the case of a 36-year-old male patient who presented with gait impairment. On examination, he had clinical findings of cervical myelopathy. The patient was evaluated with an MRI of the brain and spine, which revealed multiple spinal tumors, some causing significant canal stenosis. The spinal tumors involved the cervical, thoracic, and lumbar regions. There were both intramedullary and extramedullary tumors with an extraspinal extension. The patient's MRI brain also revealed bilateral vestibular schwannomas. His family history was negative. He subsequently underwent surgery for multiple spinal lesions followed by debulking of the right-sided vestibular schwannoma. The radiological findings of both intramedullary and extramedullary spinal tumors affecting the spinal cord and extensively involving the cervical, thoracic, and lumbar regions, and the requirement of spinal and cranial surgery concurrently make this a challenging neurosurgical case.
Copyright © 2021, Banerjee et al.

Entities:  

Keywords:  neurofibromatosis type two; retromastoid craniectomy; spinal tumors; tumor excision with laminectomy; vestibular schwannoma

Year:  2021        PMID: 35103122      PMCID: PMC8768891          DOI: 10.7759/cureus.20535

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  5 in total

Review 1.  Neurofibromatosis type 2 (NF2): diagnosis and management.

Authors:  Simon K W Lloyd; D Gareth R Evans
Journal:  Handb Clin Neurol       Date:  2013

2.  Spinal tumors in patients with neurofibromatosis type 2: MR imaging study of frequency, multiplicity, and variety.

Authors:  V F Mautner; M Tatagiba; M Lindenau; C Fünsterer; S M Pulst; M E Baser; L Kluwe; F E Zanella
Journal:  AJR Am J Roentgenol       Date:  1995-10       Impact factor: 3.959

3.  Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement.

Authors:  Rudresh Hiremath; Vishnu Dakshin; Sonal Agrawal
Journal:  Radiol Case Rep       Date:  2020-11-13

Review 4.  Neurofibromatosis type 2 (NF2): a clinical and molecular review.

Authors:  D Gareth R Evans
Journal:  Orphanet J Rare Dis       Date:  2009-06-19       Impact factor: 4.123

Review 5.  Neurofibromatosis.

Authors:  P A Gerber; A S Antal; N J Neumann; B Homey; C Matuschek; M Peiper; Wilfried Budach; E Bölke
Journal:  Eur J Med Res       Date:  2009-03-17       Impact factor: 2.175

  5 in total

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