Literature DB >> 35098358

POIROT trial: post-operative imaging after urethroplasty with peri-catheter retrograde urethrography or trial of voiding with voiding cysto-urethrography.

Wesley Verla1, Marjan Waterloos2, Mieke Waterschoot2, Christel Van Camp2, Edward Lambert2, Anne-Françoise Spinoit2, Nicolaas Lumen2.   

Abstract

PURPOSE: This study directly compares peri-catheter retrograde urethrography (pcRUG) and voiding cysto-urethrography (VCUG) as early postoperative imaging after urethroplasty and aims to assess whether pcRUG is superior at avoiding catheter reinsertion.
METHODS: This is a single-center, prospective, interventional study comparing pcRUG and VCUG after urethroplasty in a within-patient fashion. All participants were first evaluated with pcRUG and subsequently with VCUG, unless pcRUG revealed significant contrast extravasation warranting further catheter stay. The primary end-point was to assess whether pcRUG is superior at avoiding catheter reinsertion compared with VCUG. Secondary end-points included the amount of significant contrast extravasations missed on pcRUG and the differences in radiation exposure.
RESULTS: 80 patients were included in this study. Median (IQR) interval between surgery and first postoperative imaging was 16 (9-16) days. In 14/80 (18%) patients, the pcRUG showed significant contrast extravasation and catheter reinsertion was avoided, while this percentage is 0 by default for VCUG (p < 0.001). In the other 66/80 (82%) patients, a VCUG was performed and 1/66 (1.5%) of these was considered as significant contrast extravasation. Notably, 9/66 (14%) of these patients could not void during the investigation. Median (IQR) dose of radiation exposure during pcRUG and VCUG was, respectively, 120 (84-161) mGy/cm2 and 241 (169-334) mGy/cm2 (p < 0.001).
CONCLUSIONS: After urethroplasty, pcRUG is a valuable alternative for VCUG as early postoperative imaging. It has a comparable diagnostic yield, averts the risk of having to reinsert the catheter, avoids the problem of patients being unable to void during the examination and requires significantly less radiation.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Imaging; Peri-catheter; Postoperative; Urethrography; Urethroplasty; Voiding cysto-urethrography

Mesh:

Year:  2022        PMID: 35098358     DOI: 10.1007/s00345-021-03915-y

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  1 in total

1.  Retrograde pericatheter urethrogram for the post-operative evaluation of the urethra.

Authors:  B O Balogun; S O Ikuerowo; T E Akintomide; J O Esho
Journal:  Afr J Med Med Sci       Date:  2009-06
  1 in total
  1 in total

1.  Letter to the editor for the article "POIROT trial: post-operative imaging after urethroplasty with peri-catheter retrograde urethrography or trial of voiding with voiding cysto-urethrography".

Authors:  Naveen Kumar; Shrey Jain
Journal:  World J Urol       Date:  2022-04-05       Impact factor: 4.226

  1 in total

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