Literature DB >> 35095227

Combined effect of furanone fluconazole and amphotericin B against biofilms formed from Cryptococcus neoformans.

Kirishnamoorthy Meenakumari1, Giridharan Bupesh1,2.   

Abstract

It is of interest to document the combined effect of furanone fluconazole and amphotericin B against the biofilm formed by Cryptococcus neoformans. The MIC values of amphotericine B and Fluconazole were observed as 20µg/ml and 60µg/ml, respectively. The MIC for the Combination (Amphotericin B/ Fluconazole) was found to be at (15/20) µg/ml drug concentration. Thus, data shows the combined effect of furanone fluconazole and amphotericine B derivative against C. neoformans.
© 2021 Biomedical Informatics.

Entities:  

Keywords:  Cryptococcus neoformans; amphotericin B; biofilm; fluconazole

Year:  2021        PMID： 35095227      PMCID： PMC8770408          DOI： 10.6026/97320630017536

Source DB:  PubMed          Journal:  Bioinformation        ISSN： 0973-2063


  17 in total

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Review 8.  'Ready made' virulence and 'dual use' virulence factors in pathogenic environmental fungi--the Cryptococcus neoformans paradigm.

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