Literature DB >> 35086869

Recovery of Physical Function Based on Body Mass Index Following Anterior Cervical Discectomy and Fusion.

Elliot D K Cha1, Conor P Lynch1, James M Parrish1, Nathaniel W Jenkins1, Shruthi Mohan1, Cara E Geoghegan1, Caroline N Jadczak1, Kern Singh2.   

Abstract

BACKGROUND: Body mass index (BMI) serves as a risk factor for complications and poorer outcomes following anterior cervical discectomy and fusion (ACDF). This study investigates the association between BMI and Patient Reported Outcomes Measurement Information System physical function (PROMIS-PF) following ACDF.
METHODS: A prospectively maintained surgical registry was retrospectively reviewed for cervical spine surgeries between 2015 and 2019. Included patients underwent elective primary, single, or multilevel ACDF and were excluded for missing preoperative PROMIS-PF. Patients were stratified into 4 groups based on BMI score. Associations of demographic and perioperative characteristics with BMI groups were analyzed using either χ2 test or t test. PROMIS-PF was evaluated preoperatively and 6 weeks, 12 weeks, 6 months, 1 year, and 2 years postoperatively using linear regression. Delta improvement in PROMIS-PF was evaluated at all time points.
RESULTS: The 128 study cohort had 74 patients the nonobese, 27 in the Obese I, 19 in the Obese II, and 8 in the Obese III groups. The mean age was 50.0 years and 57.0% were male. Gender, diabetic status, and Charlson Comorbidity Index (CCI) significantly differed by BMI groups but did not differ by perioperative characteristics. Preoperative PROMIS-PF did not significantly differ by group. Obese II and III groups had decreased PROMIS-PF compared to Obese I and nonobese groups at 1 year and 2 years. BMI groups had significantly different delta improvement at the 12 weeks (4.1 vs 10.1 vs 1.8 vs 4.3; P = 0.044) and 2 years (9.9 vs 7.1 vs 2.3 vs 3.0; P = 0.048).
CONCLUSION: Among the assessed BMI subgroups, all experienced similar physical function scores during the preoperative and short-term time points. Patients with higher BMI demonstrated diminished physical function at long-term time points. While this study focused on evaluating obesity, longitudinal tracking of high-risk patients during the postoperative period remains important for optimal rehabilitation. LEVEL OF EVIDENCE: 4. CLINICAL RELEVANCE: High BMI may predispose patients to lengthier recovery of physical function following ACDF. This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery.
Copyright © 2021 ISASS. To see more or order reprints or permissions, see http://ijssurgery.com.

Entities:  

Keywords:  ACDF; PROMIS; body mass index; cervical spine; minimally invasive; obesity; spinal fusion

Year:  2021        PMID: 35086869      PMCID: PMC9469024          DOI: 10.14444/8143

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  42 in total

Review 1.  Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis.

Authors:  Aria Nouri; Lindsay Tetreault; Anoushka Singh; Spyridon K Karadimas; Michael G Fehlings
Journal:  Spine (Phila Pa 1976)       Date:  2015-06-15       Impact factor: 3.468

2.  Validation of Patient-Reported Outcomes Measurement Information System (PROMIS) computerized adaptive tests in cervical spine surgery.

Authors:  Barrett S Boody; Surabhi Bhatt; Aditya S Mazmudar; Wellington K Hsu; Nan E Rothrock; Alpesh A Patel
Journal:  J Neurosurg Spine       Date:  2018-01-05

3.  Minimal Clinically Important Difference and Substantial Clinical Benefit Using PROMIS CAT in Cervical Spine Surgery.

Authors:  Michael E Steinhaus; Sravisht Iyer; Francis Lovecchio; Benjamin Khechen; Daniel Stein; Thomas Ross; Jingyan Yang; Kern Singh; Todd J Albert; Darren Lebl; Russel Huang; Harvinder Sandhu; Bernard Rawlins; Frank Schwab; Virginie Lafage; Han Jo Kim
Journal:  Clin Spine Surg       Date:  2019-11       Impact factor: 1.876

4.  Improvements in Neck and Arm Pain Following an Anterior Cervical Discectomy and Fusion.

Authors:  Dustin H Massel; Benjamin C Mayo; Daniel D Bohl; Ankur S Narain; Fady Y Hijji; Steven J Fineberg; Philip K Louie; Bryce A Basques; William W Long; Krishna D Modi; Kern Singh
Journal:  Spine (Phila Pa 1976)       Date:  2017-07-15       Impact factor: 3.468

5.  Obese Class III patients at significantly greater risk of multiple complications after lumbar surgery: an analysis of 10,387 patients in the ACS NSQIP database.

Authors:  Rafael A Buerba; Michael C Fu; Jordan A Gruskay; William D Long; Jonathan N Grauer
Journal:  Spine J       Date:  2013-12-06       Impact factor: 4.166

6.  Impact of body mass index on surgical outcomes, narcotics consumption, and hospital costs following anterior cervical discectomy and fusion.

Authors:  Ankur S Narain; Fady Y Hijji; Brittany E Haws; Krishna T Kudaravalli; Kelly H Yom; Jonathan Markowitz; Kern Singh
Journal:  J Neurosurg Spine       Date:  2017-12-01

Review 7.  Current concepts of anterior cervical discectomy and fusion: a review of literature.

Authors:  Kyung-Jin Song; Byeong-Yeol Choi
Journal:  Asian Spine J       Date:  2014-08-19

Review 8.  Multilevel cervical disc replacement versus multilevel anterior discectomy and fusion: A meta-analysis.

Authors:  Ting-Kui Wu; Bei-Yu Wang; Yang Meng; Chen Ding; Yi Yang; Ji-Gang Lou; Hao Liu
Journal:  Medicine (Baltimore)       Date:  2017-04       Impact factor: 1.889

9.  Correlation of PROMIS Physical Function, Pain Interference, and Depression in Pediatric and Adolescent Patients in the Ambulatory Sports Medicine Clinic.

Authors:  Eric C Makhni; Jason E Meldau; Jacob Blanchett; Peter Borowsky; Jeffrey Stephens; Stephanie Muh; Vasilios Moutzouros
Journal:  Orthop J Sports Med       Date:  2019-06-24

10.  Impact of BMI on Complications and Satisfaction in Patients With Papillary Thyroid Cancer and Lateral Neck Metastasis.

Authors:  Qiu-Feng Jin; Qi-Gen Fang; Jin-Xing Qi; Peng Li
Journal:  Cancer Control       Date:  2019 Jan-Dec       Impact factor: 3.302

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