Literature DB >> 35086771

Bringing gene therapy to where it's needed.

Stefan Radtke1, Hans-Peter Kiem2.   

Abstract

Gene editing allows the precise modification of cells to correct genetic defects or enhance immunotherapies. A limitation is the delivery of this technology to specific cells or organs. Recently, Banskota et al. reported the use of virus-like particles (VLPs) loaded with gene-editing agents for gene therapy delivery directly inside the body.
Copyright © 2022 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  base editors; gene therapy; in vivo delivery; target specificity

Mesh:

Year:  2022        PMID: 35086771     DOI: 10.1016/j.molmed.2022.01.005

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN: 1471-4914            Impact factor:   11.951


  1 in total

Review 1.  Potential Methods of Targeting Cellular Aging Hallmarks to Reverse Osteoarthritic Phenotype of Chondrocytes.

Authors:  Yuchen He; Katelyn E Lipa; Peter G Alexander; Karen L Clark; Hang Lin
Journal:  Biology (Basel)       Date:  2022-06-30
  1 in total

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