Literature DB >> 3508198

Abnormalities of erythrocyte membrane fatty acid composition in human essential hypertension.

J D Ollerenshaw1, A M Heagerty, R F Bing, J D Swales.   

Abstract

The fatty acid content of erythrocyte plasma membrane was estimated in cells of 17 untreated hypertensive patients, and compared to that of 16 control subjects matched for age, sex and weight. Mean linoleic acid (18:2) content was significantly lower in hypertensives than controls, whereas arachidonic acid (20:4) and oleic acid (18:1) were significantly higher. These results provide further evidence for an alteration in the physiochemical structure of the plasma membrane in cells of hypertensive patients and may be related to the multiple disturbances in erythrocyte ion fluxes which have been observed.

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Year:  1987        PMID： 3508198

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN： 0950-9240            Impact factor:   3.012


  5 in total

1.  Changes in sodium-lithium countertransport correlate with changes in triglyceride levels and body mass index over 2 1/2 years of follow-up in Utah.

Authors:  S C Hunt; R R Williams; K O Ash
Journal:  Cardiovasc Drugs Ther       Date:  1990-03       Impact factor: 3.727

Review 2.  Membrane transport of ions in hypertension.

Authors:  J D Swales
Journal:  Cardiovasc Drugs Ther       Date:  1990-03       Impact factor: 3.727

3.  Changes in tissue polyunsaturated fatty acids with age, in spontaneously hypertensive rats.

Authors:  M C Delachambre; M Narce; P Asdrubal; J P Poisson
Journal:  Lipids       Date:  1998-08       Impact factor: 1.880

4.  Molecular species of membrane phospholipids containing arachidonic acid and linoleic acid contribute to the interindividual variability of red blood cell Na(+)-Li+ countertransport: in vivo and in vitro evidence.

Authors:  B Engelmann; J Duhm; U M Schönthier; S Streich; J A Op den Kamp; B Roelofsen
Journal:  J Membr Biol       Date:  1993-04       Impact factor: 1.843

Review 5.  The Implications for Cells of the Lipid Switches Driven by Protein-Membrane Interactions and the Development of Membrane Lipid Therapy.

Authors:  Manuel Torres; Catalina Ana Rosselló; Paula Fernández-García; Victoria Lladó; Or Kakhlon; Pablo Vicente Escribá
Journal:  Int J Mol Sci       Date:  2020-03-27       Impact factor: 5.923
  5 in total

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