Literature DB >> 35077687

Psychedelics.

Benjamin Kelmendi1, Alfred P Kaye1, Christopher Pittenger2, Alex C Kwan3.   

Abstract

Psychedelics are compounds that alter consciousness by acting on serotonin receptors in the brain. The term 'psychedelic', from the Greek for mind manifesting, refers to the drugs' subjective effects and was first proposed by Humphry Osmond in 1956. Other terms have been used to emphasize different aspects of the psychological experiences produced by various related compounds, including hallucinogens (perceptual), entheogens (spiritual), and empathogens or entactogens (social/emotional). The diversity in terminology reflects the existence of hundreds of potential psychedelic compounds with a spectrum of behavioral and neurobiological effects. Recent data on the effectiveness of psychedelics for treating mental illnesses has led to a resurgence of interest in their neurobiological effects. The purpose of this Primer is to provide those interested in the field of psychedelics with a concise and accessible overview of the scientific data.
Copyright © 2021 Elsevier Inc. All rights reserved.

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Year:  2022        PMID: 35077687      PMCID: PMC8830367          DOI: 10.1016/j.cub.2021.12.009

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  13 in total

Review 1.  Human hallucinogen research: guidelines for safety.

Authors:  Mw Johnson; Wa Richards; Rr Griffiths
Journal:  J Psychopharmacol       Date:  2008-07-01       Impact factor: 4.153

2.  Trial of Psilocybin versus Escitalopram for Depression.

Authors:  Robin Carhart-Harris; Bruna Giribaldi; Rosalind Watts; Michelle Baker-Jones; Ashleigh Murphy-Beiner; Roberta Murphy; Jonny Martell; Allan Blemings; David Erritzoe; David J Nutt
Journal:  N Engl J Med       Date:  2021-04-15       Impact factor: 91.245

3.  Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor.

Authors:  Kuglae Kim; Tao Che; Ouliana Panova; Jeffrey F DiBerto; Jiankun Lyu; Brian E Krumm; Daniel Wacker; Michael J Robertson; Alpay B Seven; David E Nichols; Brian K Shoichet; Georgios Skiniotis; Bryan L Roth
Journal:  Cell       Date:  2020-09-17       Impact factor: 41.582

4.  A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain.

Authors:  Charles D Nichols; Elaine Sanders-Bush
Journal:  Neuropsychopharmacology       Date:  2002-05       Impact factor: 7.853

5.  Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action.

Authors:  F X Vollenweider; M F Vollenweider-Scherpenhuyzen; A Bäbler; H Vogel; D Hell
Journal:  Neuroreport       Date:  1998-12-01       Impact factor: 1.837

Review 6.  Psychedelics.

Authors:  David E Nichols
Journal:  Pharmacol Rev       Date:  2016-04       Impact factor: 25.468

Review 7.  A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics.

Authors:  Neil K Savalia; Ling-Xiao Shao; Alex C Kwan
Journal:  Trends Neurosci       Date:  2020-12-21       Impact factor: 13.837

8.  Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo.

Authors:  Ling-Xiao Shao; Clara Liao; Ian Gregg; Pasha A Davoudian; Neil K Savalia; Kristina Delagarza; Alex C Kwan
Journal:  Neuron       Date:  2021-07-05       Impact factor: 18.688

9.  Psychedelics Promote Structural and Functional Neural Plasticity.

Authors:  Calvin Ly; Alexandra C Greb; Lindsay P Cameron; Jonathan M Wong; Eden V Barragan; Paige C Wilson; Kyle F Burbach; Sina Soltanzadeh Zarandi; Alexander Sood; Michael R Paddy; Whitney C Duim; Megan Y Dennis; A Kimberley McAllister; Kassandra M Ori-McKenney; John A Gray; David E Olson
Journal:  Cell Rep       Date:  2018-06-12       Impact factor: 9.423

10.  Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial.

Authors:  Alan K Davis; Frederick S Barrett; Darrick G May; Mary P Cosimano; Nathan D Sepeda; Matthew W Johnson; Patrick H Finan; Roland R Griffiths
Journal:  JAMA Psychiatry       Date:  2021-05-01       Impact factor: 21.596

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  2 in total

1.  Evidence on the impairing effects of Ayahuasca on fear memory reconsolidation.

Authors:  Daiane Momo Daneluz; Jeferson Machado Batista Sohn; Gabriela O Silveira; Maurício Yonamine; Cristina Aparecida Stern
Journal:  Psychopharmacology (Berl)       Date:  2022-09-07       Impact factor: 4.415

Review 2.  Unraveling the Mysteries of Mental Illness With Psilocybin.

Authors:  Robert Sotille; Herpreet Singh; Anne Weisman; Thomas Vida
Journal:  Cureus       Date:  2022-05-27
  2 in total

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