Literature DB >> 35076756

[Regression of idiopathic epiretinal membrane-Case report and consideration of the possible mechanism].

C Framme1, N Feltgen2, R Schumann3, D O Stichtenoth4, L O Hattenbach5.   

Abstract

In the presence of a symptomatic epiretinal gliosis, pars plana vitrectomy with membrane peeling to remove the membrane is usually indicated in clinical practice. According to common clinical experience, almost no independent regression of such an epiretinal membrane and thus healing of the pathology alone exists. Therefore, the unusual case of bilateral independent regression of idiopathic epiretinal gliosis and formation of a lamellar macular hole in a 73-year-old male patient is described. Considerations of the possible mechanism are presented based on the existing literature. These include separation of inflammatory versus noninflammatory membranes, possible separation of individual layers depending on the status of the posterior vitreous limiting membrane and also the possible action of proteolytic systems in the posterior vitreous region. Finally, the question arises, whether patients have to be informed about this fact before possible surgery.
© 2022. The Author(s).

Entities:  

Keywords:  Epiretinal membrane; Lamellar macular hole; SD-OCT; Vitrectomy; Vitreous detachment

Mesh:

Year:  2022        PMID: 35076756     DOI: 10.1007/s00347-022-01577-8

Source DB:  PubMed          Journal:  Ophthalmologie        ISSN: 2731-720X


  5 in total

1.  Prostaglandins alter extracellular matrix adjacent to human ciliary muscle cells in vitro.

Authors:  J D Lindsey; K Kashiwagi; F Kashiwagi; R N Weinreb
Journal:  Invest Ophthalmol Vis Sci       Date:  1997-10       Impact factor: 4.799

2.  Long-term follow-up of lamellar macular holes and pseudoholes over at least 5 years.

Authors:  K Purtskhvanidze; L Balken; T Hamann; L Wöster; C von der Burchard; J Roider; Felix Treumer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-04-06       Impact factor: 3.117

3.  Spontaneous resolution of inflammatory epiretinal membrane: Case series and review of the literature.

Authors:  Noemi Guemes-Villahoz; David Diaz-Valle; Alex Fonollosa; Maria Jimenez-Santos; Carlos Narvaez-Palazon; Alfredo Adan
Journal:  Eur J Ophthalmol       Date:  2021-07-31       Impact factor: 2.597

4.  Modulation of tissue plasminogen activator and plasminogen activator inhibitor-1 by transforming growth factor-beta in human retinal glial cells.

Authors:  Wolfgang Schacke; Karl-Friedrich Beck; Josef Pfeilschifter; Frank Koch; Lars-Olof Hattenbach
Journal:  Invest Ophthalmol Vis Sci       Date:  2002-08       Impact factor: 4.799

5.  Rapid Morphological Restoration of Normal Foveal Contour After Spontaneous Epiretinal Membrane Separation from Retina in Eye with Macular Pseudohole: A Case Report.

Authors:  Ryoma Kamada; Takeshi Iwase
Journal:  Int Med Case Rep J       Date:  2021-03-31
  5 in total

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